RAB13 and MICALL1

Number of citations of the paper that reports this interaction (PubMedID 21795389)
37

Data Source:
BioGRID (two hybrid)

		RAB13	MICALL1
Description		RAB13, member RAS oncogene family	MICAL like 1
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Cell-cell Junction Bicellular Tight Junction Synaptic Vesicle Membrane Lateral Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Trans-Golgi Network Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Insulin-responsive Compartment Cell Projection Neuron Projection Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Anchoring Junction	Cytoplasm Endosome Early Endosome Late Endosome Trans-Golgi Network Centriole Cytoskeleton Plasma Membrane Adherens Junction Cilium Cytoplasmic Side Of Endosome Membrane Membrane Late Endosome Membrane Cell Projection Recycling Endosome Membrane Ciliary Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding	Protein Binding Cytoskeletal Anchor Activity Protein-macromolecule Adaptor Activity Small GTPase Binding Identical Protein Binding Cadherin Binding Metal Ion Binding Phosphatidic Acid Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Intracellular Protein Localization Protein Kinase A Signaling Protein Transport Endosomal Transport Cortical Actin Cytoskeleton Organization Neuron Projection Development Endocytic Recycling Cellular Response To Insulin Stimulus Toll-like Receptor 4 Signaling Pathway Endothelial Cell Chemotaxis Trans-Golgi Network To Recycling Endosome Transport Localization Within Membrane Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Establishment Of Sertoli Cell Barrier Protein Localization To Cell Leading Edge	Cell Migration Involved In Sprouting Angiogenesis Protein Targeting To Membrane Endocytosis Receptor-mediated Endocytosis Protein Transport Neuron Projection Development Endocytic Recycling Slow Endocytic Recycling Protein Localization To Endosome Cilium Assembly Protein Localization To Cilium Plasma Membrane Tubulation Plasma Membrane Bounded Cell Projection Organization
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 30598549) Platelet count ( 32888494) Platelet distribution width ( 27863252 32888494)
Interacting Genes		11 interacting genes: APP MICALL1 PDE6D RAB11A RAB7A RAB8A RABGAP1L SMAD4 SMURF2 TGFBR1 VPS45	6 interacting genes: RAB13 RAB1A RFFL YWHAB YWHAG ZP3
Entrez ID		5872	85377
HPRD ID		04053	11363
Ensembl ID		ENSG00000143545	ENSG00000100139
Uniprot IDs		A0A087WWB9 P51153 Q504R6	A0A7P0T9P2 B0QY86 B0QY91 Q8N3F8
PDB IDs			2KSP
Enriched GO Terms of Interacting Partners?		Endosome Neurotransmitter Receptor Transport Endosome To Plasma Membrane Protein Transport Endocytic Recycling Cytoplasmic Vesicle Regulation Of Long-term Neuronal Synaptic Plasticity Small GTPase Binding Vesicle-mediated Transport To The Plasma Membrane Vesicle-mediated Transport SMAD Binding Regulation Of Neuronal Synaptic Plasticity Plasma Membrane Bounded Cell Projection Organization Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Plasma Membrane Protein Localization To Cilium Protein-containing Complex Localization Presynaptic Endosome Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Positive Regulation Of Extracellular Matrix Assembly Endothelial Cell Activation Neurotransmitter Receptor Transport To Postsynaptic Membrane Endosomal Transport Phagocytic Vesicle Membrane Docking Establishment Of Protein Localization To Postsynaptic Membrane Protein Transport Neurotransmitter Receptor Transport To Plasma Membrane Cell Projection Organization Endosome Membrane Vesicle-mediated Transport In Synapse Recycling Endosome Membrane Intracellular Transport Trans-Golgi Network Membrane I-SMAD Binding Myosin V Binding Establishment Of Protein Localization Golgi Apparatus Recycling Endosome Regulation Of Extracellular Matrix Assembly Endocytosis Positive Regulation Of Extracellular Matrix Organization Centriole Cardiac Epithelial To Mesenchymal Transition Cellular Localization Establishment Of Localization In Cell Activin Receptor Signaling Pathway Neuron Projection Development Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse	Establishment Of Protein Localization Intracellular Protein Localization Protein Sequestering Activity Trans-Golgi Network To Recycling Endosome Transport Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Type IV Hypersensitivity Positive Regulation Of Antral Ovarian Follicle Growth Melanosome Cellular Response To Insulin Stimulus Recycling Endosome Membrane Regulation Of T Cell Mediated Immunity Epithelial Cell Development Positive Regulation Of Immune Response Response To Insulin Protein Localization To Cell Leading Edge Establishment Of Sertoli Cell Barrier Regulation Of TOR Signaling Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Protein Kinase C Inhibitor Activity Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Positive Regulation Of Acrosomal Vesicle Exocytosis Positive Regulation Of Ovarian Follicle Development Egg Coat Formation Acrosin Binding Negative Regulation Of Binding Of Sperm To Zona Pellucida Structural Constituent Of Egg Coat Egg Coat Regulation Of Type IV Hypersensitivity Regulation Of Acrosomal Vesicle Exocytosis Endosome Cellular Response To Peptide Hormone Stimulus Regulation Of Binding Of Sperm To Zona Pellucida Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Ovarian Follicle Development Growth Hormone Secretion Insulin-responsive Compartment Protein Targeting Phosphoserine Residue Binding Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Lymphocyte Mediated Immunity Cell Development Regulation Of Adaptive Immune Response Extracellular Exosome Protein Domain Specific Binding Positive Regulation Of Hypersensitivity Virion Assembly Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Positive Regulation Of Acrosome Reaction Regulation Of Immune Response
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