RAB6A and SYTL5

Number of citations of the paper that reports this interaction (PubMedID 12051743)
0

Data Source:
HPRD (in vitro, in vivo)

		RAB6A	SYTL5
Description		RAB6A, member RAS oncogene family	synaptotagmin like 5
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Ciliary Basal Body Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle	Plasma Membrane Membrane Exocytic Vesicle
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Myosin V Binding	Protein Binding Phospholipid Binding Zinc Ion Binding Small GTPase Binding Neurexin Family Protein Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Peptidyl-cysteine Methylation Antigen Processing And Presentation Neuron Projection Development Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule Protein Localization To Golgi Membrane	Intracellular Protein Transport Exocytosis
Pathways		Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)	Anorexia nervosa ( 23568457) Erectile dysfunction and prostate cancer treatment ( 20932654)
Interacting Genes		24 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SHANK2 SYTL5 TIAM1 TMEM132D TMF1	8 interacting genes: CCDC85A CEP70 RAB27A RAB3A RAB6A TRIM54 WAC YIF1A
Entrez ID		5870	94122
HPRD ID		01543	06736
Ensembl ID		ENSG00000175582	ENSG00000147041
Uniprot IDs		A0A024R5J5 P20340 Q53ET8	Q8TDW5
PDB IDs		1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF
Enriched GO Terms of Interacting Partners?		Small GTPase Binding Golgi Apparatus Vesicle-mediated Transport Rab-protein Geranylgeranyltransferase Complex Protein Geranylgeranylation Cellular Localization Intracellular Transport Protein Prenylation Microtubule Anchoring At Microtubule Organizing Center Protein Transport GDP-dissociation Inhibitor Activity Establishment Of Localization In Cell Establishment Of Protein Localization Microtubule Anchoring Intracellular Protein Localization Minus-end-directed Organelle Transport Along Microtubule Rab Geranylgeranyltransferase Activity GTPase Activator Activity Golgi Vesicle Transport Organelle Assembly Cytosol Trans-Golgi Network Cytoplasm Positive Regulation Of Axonogenesis Microtubule-based Movement Dynactin Binding Microtubule Cytoskeleton Organization Retrograde Transport, Endosome To Golgi Dynein Complex Binding Retromer Complex Cytoskeletal Anchor Activity Small GTPase-mediated Signal Transduction Establishment Of Organelle Localization Microtubule-based Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cytosolic Transport Maintenance Of Synapse Structure Vesicle-mediated Transport To The Plasma Membrane Cytoplasmic Vesicle Mitotic Spindle Regulation Of Axonogenesis Microtubule Associated Complex Positive Regulation Of Axon Extension GTPase Binding Synaptic Vesicle Recycling Via Endosome Neuronal Cell Body Regulation Of Microtubule Cytoskeleton Organization Golgi Membrane Transport Along Microtubule Centrosome	Myosin V Binding Regulation Of Presynaptic Dense Core Granule Exocytosis Positive Regulation Of Regulated Secretory Pathway GTPase Activity Synaptic Vesicle Transport GTP Binding Establishment Of Organelle Localization Evoked Neurotransmitter Secretion Peptidyl-cysteine Methylation Cytotoxic T Cell Degranulation Positive Regulation Of Constitutive Secretory Pathway Protein Localization To Extracellular Region Organelle Localization Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Vesicle-mediated Transport Regulated Exocytosis Positive Regulation Of Exocytosis Protein Transport Establishment Of Protein Localization To Extracellular Region Protein Secretion Vesicle Localization Regulation Of Dense Core Granule Exocytosis Secretory Granule Membrane Sensory Perception Of Touch Establishment Of Vesicle Localization Antigen Processing And Presentation Endosome To Plasma Membrane Transport Vesicle Complement-dependent Cytotoxicity Regulation Of Regulated Secretory Pathway Establishment Of Protein Localization Clathrin-sculpted Glutamate Transport Vesicle Membrane Minus-end-directed Organelle Transport Along Microtubule Exosomal Secretion Acrosomal Vesicle Exocytosis Clathrin-sculpted Monoamine Transport Vesicle Membrane Regulation Of Microtubule Cytoskeleton Organization Constitutive Secretory Pathway Protein Localization To Golgi Membrane Weibel-Palade Body Regulation Of Exocytosis Regulation Of Plasma Membrane Repair Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Natural Killer Cell Degranulation Establishment Of Localization In Cell Synaptic Vesicle Maturation Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Maintenance Of Presynaptic Active Zone Structure Exocytosis Presynaptic Active Zone Organization Protein Domain Specific Binding
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