RAB6A and BICD1

Number of citations of the paper that reports this interaction (PubMedID 16473624)
0

Data Source:
BioGRID (pull down)
HPRD (two hybrid, in vitro, in vivo)

		RAB6A	BICD1
Description		RAB6A, member RAS oncogene family	BICD cargo adaptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Ciliary Basal Body Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle	Golgi Apparatus Trans-Golgi Network Centrosome Cytosol Cytoskeleton Cytoplasmic Microtubule Membrane Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm Secretory Vesicle
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Myosin V Binding	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Anchor Activity Protein Kinase Binding Small GTPase Binding Proteinase Activated Receptor Binding Dynactin Binding Dynein Intermediate Chain Binding Dynein Complex Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Peptidyl-cysteine Methylation Antigen Processing And Presentation Neuron Projection Development Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule Protein Localization To Golgi Membrane	RNA Processing Intracellular MRNA Localization Anatomical Structure Morphogenesis Virion Assembly Protein Localization To Organelle Stress Granule Assembly Constitutive Secretory Pathway Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Microtubule Cytoskeleton Organization Minus-end-directed Organelle Transport Along Microtubule Microtubule Anchoring At Microtubule Organizing Center Negative Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Localization To Centrosome
Pathways		Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)	Emphysema-related traits ( 20709820) Fourth ventricle volume ( 31530798) Intralaminar thalamic nuclei volume ( 34006833) Left ventricular mass x antihypertensive treatment interaction ( 31407531) Normalized brain volume ( 19010793) Obesity-related traits ( 23251661) Pancreatic cancer ( 20686608) Parkinson's disease ( 32201043)
Interacting Genes		24 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SHANK2 SYTL5 TIAM1 TMEM132D TMF1	15 interacting genes: ALPI CPNE4 DCTN1 DCTN2 DISC1 DSCAM DYNC1I1 FXR1 GSK3A GSK3B MAPK14 NIN PTPN23 RAB6A STAT3
Entrez ID		5870	636
HPRD ID		01543	03730
Ensembl ID		ENSG00000175582	ENSG00000151746
Uniprot IDs		A0A024R5J5 P20340 Q53ET8	A8MVZ6 F8VZX7 Q96G01
PDB IDs		1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF
Enriched GO Terms of Interacting Partners?		Small GTPase Binding Golgi Apparatus Vesicle-mediated Transport Rab-protein Geranylgeranyltransferase Complex Protein Geranylgeranylation Cellular Localization Intracellular Transport Protein Prenylation Microtubule Anchoring At Microtubule Organizing Center Protein Transport GDP-dissociation Inhibitor Activity Establishment Of Localization In Cell Establishment Of Protein Localization Microtubule Anchoring Intracellular Protein Localization Minus-end-directed Organelle Transport Along Microtubule Rab Geranylgeranyltransferase Activity GTPase Activator Activity Golgi Vesicle Transport Organelle Assembly Cytosol Trans-Golgi Network Cytoplasm Positive Regulation Of Axonogenesis Microtubule-based Movement Dynactin Binding Microtubule Cytoskeleton Organization Retrograde Transport, Endosome To Golgi Dynein Complex Binding Retromer Complex Cytoskeletal Anchor Activity Small GTPase-mediated Signal Transduction Establishment Of Organelle Localization Microtubule-based Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cytosolic Transport Maintenance Of Synapse Structure Vesicle-mediated Transport To The Plasma Membrane Cytoplasmic Vesicle Mitotic Spindle Regulation Of Axonogenesis Microtubule Associated Complex Positive Regulation Of Axon Extension GTPase Binding Synaptic Vesicle Recycling Via Endosome Neuronal Cell Body Regulation Of Microtubule Cytoskeleton Organization Golgi Membrane Transport Along Microtubule Centrosome	Axon Dynein Complex Positive Regulation Of Cellular Component Organization Regulation Of Cell Development Regulation Of Developmental Growth Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Cell Differentiation Glutamatergic Synapse Ciliary Basal Body Nervous System Development Regulation Of Glycogen (starch) Synthase Activity Regulation Of Growth Tau Protein Binding Regulation Of Axonogenesis Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Microtubule Spindle Pole Negative Regulation Of Catabolic Process Regulation Of Cell Differentiation Cell Projection Organization Cellular Response To Interleukin-3 Regulation Of Mitochondrial Membrane Permeability Regulation Of Type B Pancreatic Cell Development Centriolar Subdistal Appendage Regulation Of Neuron Projection Development Negative Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Membrane Permeability Protein Kinase Binding Regulation Of Cell Adhesion Microtubule Anchoring At Centrosome Microtubule-based Process Positive Regulation Of Neurogenesis Positive Regulation Of Axonogenesis Regulation Of Axon Extension Beta-catenin Destruction Complex Centriole-centriole Cohesion Microtubule Anchoring At Microtubule Organizing Center Plasma Membrane Bounded Cell Projection Organization Regulation Of Cellular Component Organization Positive Regulation Of Developmental Process Protein Kinase A Catalytic Subunit Binding Establishment Of Organelle Localization Organelle Organization Camera-type Eye Photoreceptor Cell Differentiation Positive Regulation Of Nervous System Development Positive Regulation Of Catabolic Process Regulation Of Multicellular Organismal Development Establishment Of Vesicle Localization
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