RRAGD and CHST15

Number of citations of the paper that reports this interaction (PubMedID 11073942)
0

Data Source:
HPRD (in vivo)

		RRAGD	CHST15
Description		Ras related GTP binding D	carbohydrate sulfotransferase 15
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Lysosome Lysosomal Membrane Centrosome Cytosol Membrane Gtr1-Gtr2 GTPase Complex	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Protein Heterodimerization Activity GTPase Binding Molecular Adaptor Activity	Protein Binding Sulfotransferase Activity Transferase Activity 3'-phosphoadenosine 5'-phosphosulfate Binding N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase Activity
	Biological Process	Intracellular Protein Localization Cellular Response To Starvation Negative Regulation Of Autophagy Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Response To Amino Acid Cellular Response To Amino Acid Stimulus Cellular Response To L-leucine Positive Regulation Of TORC1 Signaling Cellular Response To Leucine Starvation	Hexose Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process
Pathways		Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of PTEN gene transcription Amino acids regulate mTORC1	CS-GAG biosynthesis DS-GAG biosynthesis
Drugs
Diseases
GWAS		Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163) Glomerular filtration rate ( 29403010)	Blood protein levels ( 30072576) Daytime sleep phenotypes ( 27126917) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		4 interacting genes: CHST15 ITGB8 NOL8 RRAGB	4 interacting genes: HCK LYN MEOX2 RRAGD
Entrez ID		58528	51363
HPRD ID		12199	12203
Ensembl ID		ENSG00000025039	ENSG00000182022
Uniprot IDs		Q9NQL2	B4DH74 Q7LFX5
PDB IDs		2Q3F
Enriched GO Terms of Interacting Partners?		Integrin Alphav-beta8 Complex Guanyl Ribonucleotide Binding N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase Activity Langerhans Cell Differentiation Gtr1-Gtr2 GTPase Complex Extracellular Matrix Protein Binding	Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Negative Regulation Of Inflammatory Response To Antigenic Stimulus Lipopolysaccharide-mediated Signaling Pathway Peptidyl-tyrosine Phosphorylation Non-membrane Spanning Protein Tyrosine Kinase Activity Fc Receptor Signaling Pathway Lysosome Regulated Exocytosis Cytoplasmic Side Of Plasma Membrane Response To Amino Acid Protein Autophosphorylation Protein Tyrosine Kinase Activity Positive Regulation Of Oligodendrocyte Progenitor Proliferation Innate Immune Response-activating Signaling Pathway Membrane Raft Respiratory Burst After Phagocytosis Negative Regulation Of Immune Response Leukocyte Migration Leukocyte Migration Involved In Immune Response Activation Of Innate Immune Response Negative Regulation Of Inflammatory Response Exocytosis Platelet Degranulation Histamine Secretion By Mast Cell Negative Regulation Of Mast Cell Proliferation Fc Receptor Mediated Inhibitory Signaling Pathway Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Postsynaptic Specialization, Intracellular Component Positive Regulation Of Mast Cell Proliferation Integrin Alpha2-beta1 Complex Tolerance Induction To Self Antigen Positive Regulation Of Dendritic Cell Apoptotic Process Somite Specification Gtr1-Gtr2 GTPase Complex Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Oligodendrocyte Progenitor Proliferation Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Eosinophil Differentiation Glycosphingolipid Binding Interleukin-5-mediated Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Defense Response Phosphatidylinositol 3-kinase Activator Activity C-X-C Chemokine Receptor CXCR4 Signaling Pathway Histamine Secretion Positive Regulation Of Innate Immune Response Mitochondrial Crista Regulation Of Mast Cell Proliferation
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