ZFAT and KLHL20

Number of citations of the paper that reports this interaction (PubMedID 26687681)
0

Data Source:
BioGRID (two hybrid)

		ZFAT	KLHL20
Description		zinc finger and AT-hook domain containing	kelch like family member 20
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Actin Cytoskeleton PML Body Axon Dendrite Cul3-RING Ubiquitin Ligase Complex Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding Type II Interferon Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Hematopoietic Progenitor Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Hemopoiesis Positive Regulation Of Transcription By RNA Polymerase II	Golgi To Endosome Transport Cytoskeleton Organization Protein Transport Protein Ubiquitination Response To Interferon-alpha Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Ubiquitination
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		A body shape index ( 34021172) Appendicular lean mass ( 33097823) Chronotype ( 30696823) Early-onset Parkinson's disease ( 28256260) Eosinophil percentage of white cells ( 32888494) Heel bone mineral density ( 30598549) Height ( 25282103 31562340 20881960 25429064) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 34021172 25673412) Iron status biomarkers (iron levels) ( 28334935) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Pulse pressure ( 30578418) Red blood cell count ( 32888494) Response to antidepressants (symptom remission) ( 29160301) Response to SSRI (symptom remission) ( 29160301) Short-term memory (visuospatial task) ( 29970928) Systolic blood pressure ( 28135244 30578418) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Feeling miserable ( 29500382)
Interacting Genes		4 interacting genes: HSPB1 KLHL20 TULP3 YY1AP1	82 interacting genes: ABLIM1 ACTA1 AOC1 ARHGAP10 ARHGEF11 ARHGEF12 ARHGEF19 ATG9A BCL6 BECN1 BEX1 BEX2 BRINP2 C1orf216 C21orf58 CASP8AP2 CC2D1A CEP126 CIDEC CIMIP1 CLCNKA COL8A1 CORO7 CRK CRMP1 DMAC2 DUSP21 ECT2 EIF3F ENKD1 EPAS1 ERG28 F13A1 FBLN1 FHL2 FIZ1 GBE1 GBP2 GMCL1 HR IVNS1ABP JMJD1C KLHL38 KLHL9 LMO2 LRIF1 LUC7L2 MESD MTNR1A NECAB3 NEDD9 NISCH NTAQ1 NUDCD3 NUP160 ORC4 PAPPA PDPK1 PGLS PIK3C3 PIN1 PML PNKD POLR3D PRKAG1 PRMT6 RACK1 RANBP3 RECK RFC2 SGTA SLC13A5 SLC3A2 STK16 SUV39H1 SVEP1 TFAP2D TNPO2 ULK1 USP20 VPS54 ZFAT
Entrez ID		57623	27252
HPRD ID		11712	13918
Ensembl ID		ENSG00000066827	ENSG00000076321
Uniprot IDs		B7Z6H1 E9PBN4 F8W7M8 Q4KMQ4 Q6PJQ2 Q9P243	Q9Y2M5
PDB IDs		2ELM 2ELN 2ELO 2ELP 2ELQ 2ELR 2ELS 2ELT 2ELU 2ELV 2RSH 2RSI 2RSJ 2RUT 2RUU 2RUV 2RUW 2RUX 2RUY 2RUZ 2RV0 2RV1 2RV2 2RV3 2RV6 2RV7	5YQ4 6GY5 8CIA
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Kinase C Signaling Protein Kinase C Inhibitor Activity Intraciliary Transport Particle A Binding Bronchus Morphogenesis Protein K33-linked Ubiquitination Type II Interferon Binding Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Regulation Of Protein Kinase C Signaling Positive Regulation Of Endothelial Cell Chemotaxis Protein Transport Along Microtubule Anterograde Axonal Protein Transport Contractile Muscle Fiber 9+0 Non-motile Cilium Neural Tube Formation Embryonic Neurocranium Morphogenesis Embryonic Camera-type Eye Development Dorsal/ventral Neural Tube Patterning Golgi To Endosome Transport Ino80 Complex Ganglion Development	Protein Binding Midbody Phagophore Assembly Site Regulation Of Cytokinesis Cytoplasm Cellular Response To Glucose Starvation Phosphatidylinositol 3-kinase Complex, Class III, Type II Phosphatidylinositol 3-kinase Complex, Class III, Type I
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