ZNF398 and CIB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF398	CIB3
Description		zinc finger protein 398	calcium and integrin binding family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Magnesium Ion Binding Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription	Calcium Ion Homeostasis
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Eosinophil count ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494) Sum eosinophil basophil counts ( 27863252)	Lymphocyte count ( 32888494)
Interacting Genes		23 interacting genes: - AIRIM AQP1 CABP5 CHD2 CHPF2 CIB3 CLK2 DGCR6 ELMO1 EMD ESR1 GPATCH2L MAGOHB MFAP1 NCDN NDE1 NUDT22 OPTN PLEKHF2 SMARCB1 TRIM41 ZNF783	53 interacting genes: ARMC8 BEND7 C17orf50 ENOX2 GMCL1 KASH5 KLF17 LNX1 MEOX1 MEOX2 NANOS3 NME4 PAX5 PAX6 POLR2G POU6F2 RBAK REL SCNM1 SERTAD1 SLPI SP3 SP4 SYPL1 TACC3 TLE5 TRAF5 TRIM14 TRIM2 ZBTB43 ZC2HC1C ZFP1 ZFP57 ZNF146 ZNF177 ZNF180 ZNF19 ZNF276 ZNF317 ZNF329 ZNF398 ZNF426 ZNF552 ZNF559-ZNF177 ZNF578 ZNF597 ZNF620 ZNF664 ZNF688 ZNF774 ZNF835 ZSCAN4 ZSCAN5A
Entrez ID		57541	117286
HPRD ID		18336	16713
Ensembl ID		ENSG00000197024	ENSG00000141977
Uniprot IDs		A0A090N7S8 A0A090N8F2 B4DXA9 Q8TD17	Q96Q77
PDB IDs			6WU5 6WU7 6WUD
Enriched GO Terms of Interacting Partners?			DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Zinc Ion Binding DNA Binding Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Metal Ion Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Sequence-specific Double-stranded DNA Binding Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Protein Binding DNA-binding Transcription Factor Activity RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Somite Specification DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific DNA Binding HMG Box Domain Binding Embryonic Camera-type Eye Morphogenesis Segment Specification Somite Development Chromatin
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