TRPC7 and MX1

Number of citations of the paper that reports this interaction (PubMedID 15757897)
0

Data Source:
HPRD (in vivo, in vitro)

		TRPC7	MX1
Description		transient receptor potential cation channel subfamily C member 7	MX dynamin like GTPase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Plasma Membrane Membrane Cation Channel Complex Perinuclear Region Of Cytoplasm	Nucleus Nuclear Envelope Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Microtubule Plasma Membrane Membrane Nuclear Membrane Synapse Perinuclear Region Of Cytoplasm Presynapse
	Molecular Function	Monoatomic Ion Channel Activity Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Manganese Ion Transport Single Fertilization Monoatomic Ion Transmembrane Transport Regulation Of Cytosolic Calcium Ion Concentration Transmembrane Transport Calcium Ion Transmembrane Transport	Immune System Process Apoptotic Process Defense Response Signal Transduction Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Interleukin-27-mediated Signaling Pathway Antiviral Innate Immune Response
Pathways		Effects of PIP2 hydrolysis Elevation of cytosolic Ca2+ levels TRP channels Role of second messengers in netrin-1 signaling	ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Body fat percentage ( 31752434) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) Interleukin-6 levels in non-alcoholic fatty liver disease x mastiha supplementation interaction ( 34025683) Sleep duration (short sleep) ( 30846698)
Interacting Genes		4 interacting genes: ITPR3 MX1 TRPC3 TRPC6	55 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CCL16 CD5 CHD3 DAXX DCP2 EPM2AIP1 FANCA FXR1 GGPS1 GMEB1 GPC4 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 MX2 NDC80 NDUFV3 PDE9A PGRMC1 PIAS1 PIAS2 PLRG1 PRDX6 PSD3 PSG9 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZFP36 ZNF251 ZNF623
Entrez ID		57113	4599
HPRD ID		18228	00919
Ensembl ID		ENSG00000069018	ENSG00000157601
Uniprot IDs		Q70T25 Q9HCX4	H9KVC7 P20591
PDB IDs			3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
Enriched GO Terms of Interacting Partners?		Inositol 1,4,5 Trisphosphate Binding Calcium Channel Activity Store-operated Calcium Channel Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Monoatomic Ion Channel Activity Calcium Ion Transmembrane Transport Cation Channel Complex Calcium Ion Homeostasis Calcium Ion Transport Inorganic Ion Homeostasis Regulation Of Cytosolic Calcium Ion Concentration Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Metal Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Positive Regulation Of Calcium Ion Transport Single Fertilization Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport Response To Calcium Ion Fertilization Chemical Homeostasis Monoatomic Ion Transport Inositol 1,4,5-trisphosphate-gated Calcium Channel Activity Inositol Hexakisphosphate Binding Intracellular Calcium Ion Homeostasis Positive Regulation Of Monoatomic Ion Transport Sensory Perception Of Umami Taste Sensory Perception Of Sweet Taste Regulation Of Calcium Ion Transport Transmembrane Transport Inositol 1,3,4,5 Tetrakisphosphate Binding Sensory Perception Of Bitter Taste Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Homeostatic Process Regulation Of Monoatomic Ion Transmembrane Transport Interleukin-27-mediated Signaling Pathway Slit Diaphragm Intracellularly Gated Calcium Channel Activity Platelet Dense Tubular Network Membrane Negative Regulation Of Dendrite Morphogenesis Response To Metal Ion Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Metal Ion Transport Calcium-activated Cation Channel Activity Response To Type I Interferon Positive Regulation Of Calcium Ion Transport Into Cytosol	Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding Cation Channel Complex PML Body Regulation Of Cytosolic Calcium Ion Concentration Calcium Channel Activity Transcription Corepressor Activity Cytoplasmic Ribonucleoprotein Granule SUMO Ligase Activity Actinin Binding Negative Regulation Of Cytokine Production Involved In Inflammatory Response Monoatomic Ion Channel Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Intracellular Calcium Ion Homeostasis SUMO Transferase Activity Calcium Ion Transmembrane Transport Calcium Ion Homeostasis Regulation Of Presynapse Organization Regulation Of Presynapse Assembly Positive Regulation Of Cell-cell Adhesion Negative Regulation Of RNA Metabolic Process Calcium Ion Transport Regulation Of Cytokine Production Involved In Inflammatory Response Nucleus Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Cell Development Regulation Of T Cell Activation Identical Protein Binding Regulation Of T Cell Differentiation Intracellular Monoatomic Cation Homeostasis Associative Learning Inorganic Ion Homeostasis Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Macromolecule Biosynthetic Process Protein Homodimerization Activity Intracellular Monoatomic Ion Homeostasis Negative Regulation Of Dendrite Morphogenesis Positive Regulation Of Cell Differentiation Regulation Of Synapse Organization Ubiquitin Protein Ligase Binding Regulation Of Multicellular Organismal Development Positive Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Nuclear Envelope Lumen SUMO Binding Synapse Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing
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