MX1 and TRPC5

Number of citations of the paper that reports this interaction (PubMedID 15757897)
0

Data Source:
HPRD (in vitro, in vivo)

		MX1	TRPC5
Description		MX dynamin like GTPase 1	transient receptor potential cation channel subfamily C member 5
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Microtubule Plasma Membrane Membrane Nuclear Membrane Synapse Perinuclear Region Of Cytoplasm Presynapse	Plasma Membrane Membrane Dendrite Growth Cone Cation Channel Complex Calcium Channel Complex Neuronal Cell Body Presynapse
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding	Actin Binding Monoatomic Ion Channel Activity Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Clathrin Binding Actinin Binding Metal Ion Binding ATPase Binding Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Immune System Process Apoptotic Process Defense Response Signal Transduction Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Interleukin-27-mediated Signaling Pathway Antiviral Innate Immune Response	Monoatomic Ion Transport Calcium Ion Transport Positive Regulation Of Cytosolic Calcium Ion Concentration Nervous System Development Positive Regulation Of Cell Population Proliferation Neuron Differentiation Monoatomic Ion Transmembrane Transport Positive Regulation Of Neuron Differentiation Positive Regulation Of Axon Extension Negative Regulation Of Dendrite Morphogenesis Neuron Apoptotic Process Regulation Of Cytosolic Calcium Ion Concentration Transmembrane Transport Calcium Ion Transmembrane Transport Phosphatidylserine Exposure On Apoptotic Cell Surface Regulation Of Membrane Hyperpolarization
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	TRP channels Role of second messengers in netrin-1 signaling
Drugs
Diseases
GWAS			Smoking behavior ( 19247474)
Interacting Genes		55 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CCL16 CD5 CHD3 DAXX DCP2 EPM2AIP1 FANCA FXR1 GGPS1 GMEB1 GPC4 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 MX2 NDC80 NDUFV3 PDE9A PGRMC1 PIAS1 PIAS2 PLRG1 PRDX6 PSD3 PSG9 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZFP36 ZNF251 ZNF623	10 interacting genes: DRD2 ENKUR ITPR3 MX1 NHERF1 PLS3 STMN2 STMN3 TRPC1 TRPC4
Entrez ID		4599	7224
HPRD ID		00919	02273
Ensembl ID		ENSG00000157601	ENSG00000072315
Uniprot IDs		H9KVC7 P20591	Q9UL62
PDB IDs		3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM	6YSN 7D4P 7D4Q 7E4T 7WDB 7X6C 7X6I 8GVW 8GVX
Enriched GO Terms of Interacting Partners?		Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding Cation Channel Complex PML Body Regulation Of Cytosolic Calcium Ion Concentration Calcium Channel Activity Transcription Corepressor Activity Cytoplasmic Ribonucleoprotein Granule SUMO Ligase Activity Actinin Binding Negative Regulation Of Cytokine Production Involved In Inflammatory Response Monoatomic Ion Channel Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Intracellular Calcium Ion Homeostasis SUMO Transferase Activity Calcium Ion Transmembrane Transport Calcium Ion Homeostasis Regulation Of Presynapse Organization Regulation Of Presynapse Assembly Positive Regulation Of Cell-cell Adhesion Negative Regulation Of RNA Metabolic Process Calcium Ion Transport Regulation Of Cytokine Production Involved In Inflammatory Response Nucleus Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Cell Development Regulation Of T Cell Activation Identical Protein Binding Regulation Of T Cell Differentiation Intracellular Monoatomic Cation Homeostasis Associative Learning Inorganic Ion Homeostasis Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Macromolecule Biosynthetic Process Protein Homodimerization Activity Intracellular Monoatomic Ion Homeostasis Negative Regulation Of Dendrite Morphogenesis Positive Regulation Of Cell Differentiation Regulation Of Synapse Organization Ubiquitin Protein Ligase Binding Regulation Of Multicellular Organismal Development Positive Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Nuclear Envelope Lumen SUMO Binding Synapse Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing	Inositol 1,4,5 Trisphosphate Binding Acid Secretion Inorganic Ion Homeostasis Calcium Ion Transmembrane Transport Calcium Ion Homeostasis Calcium Ion Transport Phospholipase C-activating Dopamine Receptor Signaling Pathway Metal Ion Transport Calcium Channel Activity Store-operated Calcium Channel Activity Gamma-aminobutyric Acid Transport Monoatomic Cation Transport Cation Channel Complex Microtubule Depolymerization Regulation Of Sequestering Of Calcium Ion Chemical Homeostasis G Protein-coupled Dopamine Receptor Signaling Pathway Monoatomic Ion Transport Monoatomic Ion Channel Activity Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Intracellular Calcium Ion Homeostasis Intracellular Chemical Homeostasis Protein Depolymerization Microtubule Polymerization Or Depolymerization Transmembrane Transport Inorganic Cation Transmembrane Transport Monoatomic Cation Transmembrane Transport Cellular Homeostasis Carboxylic Acid Transport Organic Acid Transport Homeostatic Process Inorganic Ion Transmembrane Transport Regulation Of Cytosolic Calcium Ion Concentration Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Sequestering Of Calcium Ion Structural Constituent Of Presynaptic Actin Cytoskeleton Renal Phosphate Ion Absorption Tubulin Binding Monoatomic Ion Transmembrane Transport Regulation Of Sodium Ion Transport Response To Metal Ion Microtubule-based Process Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Organic Anion Transport Regulation Of Metal Ion Transport G Protein-coupled Receptor Complex Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Phenol-containing Compound Metabolic Process Apical Part Of Cell
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?