COQ8A and CCDC34

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		COQ8A	CCDC34
Description		coenzyme Q8A	coiled-coil domain containing 34
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Membrane Extrinsic Component Of Mitochondrial Inner Membrane Mitochondrial Membrane	Cilium Motile Cilium Cell Projection Sperm Midpiece
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Binding ATP Binding Enzyme Activator Activity Kinase Activity Transferase Activity ADP Binding	Protein Binding
	Biological Process	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation	Spermatogenesis
Pathways		Ubiquinol biosynthesis
Drugs		Fostamatinib
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3) Coenzyme Q10 deficiency
GWAS			Body mass index ( 29273807) Bone mineral density (paediatric, skull) ( 24945404) Dental caries (decayed, missing and filled teeth) ( 31533690) Heel bone mineral density ( 30598549) Waist circumference ( 28552196)
Interacting Genes		27 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 LDAF1 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM239 TPD52L2 UBC	2 interacting genes: COQ8A TMEM86B
Entrez ID		56997	91057
HPRD ID		07375	14868
Ensembl ID		ENSG00000163050	ENSG00000109881
Uniprot IDs		Q8NI60	Q96HJ3
PDB IDs		4PED 5I35 7UDP 7UDQ
Enriched GO Terms of Interacting Partners?			D-lysine 5,6-aminomutase Activity Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Extrinsic Component Of Mitochondrial Inner Membrane Ubiquinone Metabolic Process Quinone Metabolic Process Ubiquinone Biosynthetic Process Ether Lipid Metabolic Process Phosphatidylcholine Acyl-chain Remodeling Ketone Biosynthetic Process ADP Binding Phosphate-containing Compound Metabolic Process Phosphatidylcholine Metabolic Process Enzyme Activator Activity Ketone Metabolic Process
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