NMUR2 and KRTAP13-1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		NMUR2	KRTAP13-1
Description		neuromedin U receptor 2	keratin associated protein 13-1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Neuromedin U Receptor Activity G Protein-coupled Receptor Activity Intracellularly Calcium-gated Chloride Channel Activity Protein Binding GTP Binding Neuropeptide Receptor Activity Neuromedin U Binding	Structural Molecule Activity
	Biological Process	Reduction Of Food Intake In Response To Dietary Excess Chloride Transport Regulation Of Smooth Muscle Contraction Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Cell-cell Signaling Central Nervous System Development Grooming Behavior Feeding Behavior Response To Pain Arachidonate Secretion Positive Regulation Of Calcium-mediated Signaling Chloride Transmembrane Transport
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Keratinization
Drugs
Diseases
GWAS		Ability to confide in someone ( 29970889) Adult body size ( 32376654) Bipolar disorder ( 33169155) Bipolar disorder and schizophrenia ( 22688191) Body size at age 10 ( 32376654) Caffeine consumption from tea ( 33287642) Chronotype ( 30696823) Feeling lonely ( 29500382) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Manganese levels ( 26025379) Metabolite levels ( 23823483) Morning person ( 30696823) Number of sexual partners ( 30643258) Optic nerve measurement (cup area) ( 20395239) Periodontitis (PAL4Q3) ( 24024966) Schizophrenia ( 28991256) Sedentary behaviour duration ( 30531941) Subjective well-being ( 27089181)	Treatment resistant depression ( 30468137)
Interacting Genes		6 interacting genes: ADAMTSL4 KRTAP13-1 NMU NOTCH2NLA TCF4 TRAF2	43 interacting genes: ARMC7 ATXN1L BAG4 BANF2 BCL6 CFAP206 CHRD COL8A1 CRACR2A FAM221B GLRX3 KLHL38 KRT34 KRTAP10-3 KRTAP10-5 KRTAP12-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LONRF1 MAPKBP1 MEIS2 NEK6 NMUR2 NOXA1 OTX1 PITX1 POU4F2 PROP1 PRR13 PSPC1 RANBP3 RBPMS RIN1 SCAMP1 STK16 TBC1D10C TBX6 TEKT4 TNS2 UBQLN2 VENTX YTHDF1
Entrez ID		56923	140258
HPRD ID		12003	10570
Ensembl ID		ENSG00000132911	ENSG00000198390
Uniprot IDs		Q9GZQ4	Q8IUC0
PDB IDs		7W55 7W57 7XK8
Enriched GO Terms of Interacting Partners?		TORC2 Complex Disassembly Neuromedin U Receptor Binding Type 2 Neuromedin U Receptor Binding Negative Regulation Of Gastric Emptying Positive Regulation Of Stomach Fundus Smooth Muscle Contraction Type 1 Neuromedin U Receptor Binding Pigment Cell Development TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Positive Regulation Of Prolactin Secretion TFIIB-class Transcription Factor Binding Beta-catenin-TCF7L2 Complex Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex Negative Regulation Of Gastric Acid Secretion Positive Regulation Of Sensory Perception Of Pain Regulation Of Gastric Motility Regulation Of Grooming Behavior Negative Regulation Of Eating Behavior CD27 Signaling Pathway Positive Regulation Of Gastro-intestinal System Smooth Muscle Contraction Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding Regulation Of Gastric Acid Secretion Negative Regulation Of Feeding Behavior Interstitial Matrix Regulation Of Eating Behavior Gastric Acid Secretion Thioesterase Binding CD40 Signaling Pathway Negative Regulation Of Glial Cell Apoptotic Process Interleukin-17-mediated Signaling Pathway CD40 Receptor Complex Positive Regulation Of Heat Generation Positive Regulation Of JUN Kinase Activity Beta-catenin-TCF Complex TORC2 Signaling Cellular Response To Nitric Oxide Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Mitogen-activated Protein Kinase Kinase Kinase Binding Positive Regulation Of Systemic Arterial Blood Pressure Cellular Response To Reactive Nitrogen Species	Keratin Filament Intermediate Filament
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