IFT46 and NLRX1

		IFT46	NLRX1
Description		intraflagellar transport 46	NLR family member X1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Microtubule Organizing Center Cytoskeleton Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Cell Projection Ciliary Tip Plasma Membrane Bounded Cell Projection	Mitochondrion Mitochondrial Outer Membrane Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding	Nucleotide Binding Protein Binding ATP Binding
	Biological Process	Smoothened Signaling Pathway Intraciliary Anterograde Transport Intraciliary Transport Protein Stabilization Cilium Assembly	Immune System Process Negative Regulation Of Macrophage Cytokine Production Negative Regulation Of Interferon-beta Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of RIG-I Signaling Pathway Negative Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Negative Regulation Of Innate Immune Response Negative Regulation Of Inflammatory Response
Pathways		Intraflagellar transport Intraflagellar transport	DDX58/IFIH1-mediated induction of interferon-alpha/beta Negative regulators of DDX58/IFIH1 signaling Regulation of NF-kappa B signaling
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 32154731)	Mean reticulocyte volume ( 32888494)
Interacting Genes		4 interacting genes: FBXL17 MTDH NLRX1 UBXN10	9 interacting genes: ABCG4 BUD13 C1QTNF5 IFT46 NHERF4 SARM1 SCN3B TMEM25 TMPRSS4
Entrez ID		56912	79671
HPRD ID		07967	17640
Ensembl ID		ENSG00000118096	ENSG00000160703
Uniprot IDs		Q9NQC8	A0A9L9PX86 Q86UT6
PDB IDs			3UN9
Enriched GO Terms of Interacting Partners?			NADP+ Nucleosidase Activity Negative Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway Extrinsic Component Of Synaptic Membrane NAD+ Nucleosidase Activity Negative Regulation Of Growth Rate Guanylate Cyclase Inhibitor Activity RES Complex Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway NAD+ Catabolic Process ABC-type Sterol Transporter Activity
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