COXFA4L2 and QTRT1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COXFA4L2	QTRT1
Description		cytochrome c oxidase hypoxia associated subunit FA4L2	queuine tRNA-ribosyltransferase catalytic subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Respiratory Chain Complex IV	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Membrane Cytoplasmic Side Of Mitochondrial Outer Membrane Protein-containing Complex TRNA-guanine Transglycosylase Complex Transferase Complex
	Molecular Function		Protein Binding TRNA-guanosine(34) Queuine Transglycosylase Activity Transferase Activity Glycosyltransferase Activity Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process		TRNA Wobble Guanine Modification TRNA Modification TRNA Processing
Pathways			tRNA modification in the nucleus and cytosol
Drugs		NADH
Diseases
GWAS			Bipolar disorder ( 31043756) FEV1 ( 30804560) Inflammatory skin disease ( 25574825) Lung function (FVC) ( 30804560) Psoriasis ( 25903422)
Interacting Genes		14 interacting genes: ANXA9 C6orf62 COMMD8 DYNLL1 EIF3C ERG28 KAT5 KCNA4 LUC7L2 NUFIP2 PRKN QTRT1 SLC35F6 UBR1	8 interacting genes: COPS6 COXFA4L2 LCOR RHOU SETDB1 SH3GL3 UNC119 ZBTB16
Entrez ID		56901	81890
HPRD ID		14249	17943
Ensembl ID		ENSG00000185633	ENSG00000213339
Uniprot IDs		Q9NRX3	Q71RF8 Q9BXR0
PDB IDs			6H42 6H45 7NQ4 8OMR
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Clathrin-dependent Endocytosis Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Receptor-mediated Endocytosis Transcription Corepressor Binding Negative Regulation Of Endocytosis Endocytosis Type 2 Angiotensin Receptor Binding Negative Regulation Of Caveolin-mediated Endocytosis Regulation Of Receptor-mediated Endocytosis Male Germ-line Stem Cell Asymmetric Division Germ-line Stem Cell Division Positive Regulation Of NK T Cell Differentiation Histone H3K9 Trimethyltransferase Activity Central Nervous System Development
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