DMAP1 and GINS4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DMAP1	GINS4
Description		DNA methyltransferase 1 associated protein 1	GINS complex subunit 4
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GO Annotations	Cellular Component	Nucleosome Swr1 Complex Nucleus Nucleoplasm Replication Fork Chromosome Cytoplasm Cytosol NuA4 Histone Acetyltransferase Complex	GINS Complex Nucleus Nucleoplasm Chromosome Cytoplasm CMG Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Positive Regulation Of Protein Import Into Nucleus Regulation Of Apoptotic Process Response To Ethanol Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair	Double-strand Break Repair Via Break-induced Replication Inner Cell Mass Cell Proliferation DNA Replication DNA-templated DNA Replication
Pathways		HATs acetylate histones	Unwinding of DNA Unwinding of DNA
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		41 interacting genes: ARFIP2 BFSP2 BTG3 C1orf216 CCHCR1 CDCA7L CEBPB DAXX DNMT1 DRC4 EXOC8 GINS4 HDAC2 HSF2BP HSPB1 ING1 KRT75 LMNB1 LRSAM1 MIS18A MNAT1 MORF4L1 MRGBP NAP1L2 OGT PFDN1 PIBF1 RGS6 SAAL1 SBK3 SUOX TCEANC TCHP TLK2 TOMM34 TRIM21 TSG101 TSGA10IP TXLNA TXLNB URI1	13 interacting genes: - BIN3 CTNNBIP1 DMAP1 GINS2 IDO2 KIF16B LHX8 PBX4 POLA1 POLD1 POLE PPP1R13B
Entrez ID		55929	84296
HPRD ID		05465	11583
Ensembl ID		ENSG00000178028	ENSG00000147536
Uniprot IDs		Q9NPF5	Q9BRT9
PDB IDs		3HM5 4IEJ 8QR1 8X15 8X19 8X1C 8XVG 8XVT 9C57 9C62 9C6N	2E9X 2EHO 2Q9Q 6XTX 6XTY 7PFO 7PLO 8B9D 8OK2
Enriched GO Terms of Interacting Partners?		Sin3-type Complex Chromatin Organization Negative Regulation Of Stem Cell Population Maintenance	DNA Polymerase Activity DNA-directed DNA Polymerase Activity DNA Replication Proofreading DNA Synthesis Involved In DNA Repair Leading Strand Elongation DNA Replication DNA-templated DNA Replication Nucleotide-excision Repair, DNA Gap Filling DNA Repair DNA Strand Elongation Involved In DNA Replication Nucleotidyltransferase Activity DNA Biosynthetic Process Base-excision Repair, Gap-filling DNA Strand Elongation DNA Metabolic Process DNA Damage Response 4 Iron, 4 Sulfur Cluster Binding Actin Cortical Patch Localization Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Iron-sulfur Cluster Binding Beta-catenin-ICAT Complex Indoleamine 2,3-dioxygenase Activity Lagging Strand Elongation DNA Synthesis Involved In UV-damage Excision Repair Unidimensional Cell Growth Tryptophan 2,3-dioxygenase Activity Mitotic DNA Replication Initiation Nucleobase-containing Compound Biosynthetic Process Alpha DNA Polymerase:primase Complex Error-free Translesion Synthesis Delta DNA Polymerase Complex Epsilon DNA Polymerase Complex Single-stranded DNA 3'-5' DNA Exonuclease Activity GINS Complex Myoblast Migration Involved In Skeletal Muscle Regeneration Response To Ethanol L-tryptophan Catabolic Process To Kynurenine Cellular Response To Stress DNA Replication, Synthesis Of Primer Nucleotide-excision Repair Complex Negative Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Transcription Initiation By RNA Polymerase II
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