ZC3H15 and DRG1

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (two hybrid, affinity chromatography technology, proximity labelling technology, affinity chromatography technology, affinity chromatography technology)

		ZC3H15	DRG1
Description		zinc finger CCCH-type containing 15	developmentally regulated GTP binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Body
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Cadherin Binding Metal Ion Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Hydrolase Activity Potassium Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Cytoplasmic Translation Cytokine-mediated Signaling Pathway Positive Regulation Of GTPase Activity	Cytoplasmic Translation Positive Regulation Of Microtubule Polymerization Regulation Of Mitotic Spindle Assembly
Pathways		Protein hydroxylation	Protein hydroxylation
Drugs
Diseases
GWAS		PR interval ( 32439900)	Fish- and plant-related diet ( 32066663) Neutrophil count ( 27863252 32888494) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Sum basophil neutrophil counts ( 27863252) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		7 interacting genes: C8orf33 CEBPA CSNK2A1 DRG1 OGT TNNT1 ZNF804A	19 interacting genes: CAPNS1 CEBPA CFTR CLDN1 COIL LNX1 LYL1 MEOX2 NF2 PHC2 PTEN RWDD1 SKIL SRPK2 SSX2IP STK16 TAL1 UBE2I ZC3H15
Entrez ID		55854	4733
HPRD ID		13988	16034
Ensembl ID		ENSG00000065548	ENSG00000185721
Uniprot IDs		Q8WU90	Q9Y295
PDB IDs			2EKI
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Sin3-type Complex Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Proteolysis Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Slow-twitch Skeletal Muscle Fiber Contraction Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Chromatin DNA Binding Protein Localization To Vacuole Response To Vitamin B2 C/EBP Complex Regulation Of Translational Initiation CHOP-C/EBP Complex Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Protein Catabolic Process Cytoplasmic Translation Protein O-acetylglucosaminyltransferase Activity Dendritic Microtubule Response To Nutrient White Fat Cell Proliferation Negative Regulation Of Proteolysis Troponin T Binding Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Positive Regulation Of Aggrephagy Macroautophagy Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Translation Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Positive Regulation Of Proteolysis Carbohydrate Homeostasis Response To Phenylpropanoid Glucose Homeostasis Transition Between Fast And Slow Fiber Carbon Catabolite Regulation Of Transcription Positive Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Fat Cell Proliferation	Developmental Maturation Response To Ketone Protein-containing Complex PDZ Domain Binding Definitive Hemopoiesis Lens Fiber Cell Differentiation Synapse Maturation Anatomical Structure Formation Involved In Morphogenesis PML Body Granulocyte Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Response To Dexamethasone Regulation Of Cell Cycle Cell Maturation Enzyme Binding 14-3-3 Protein Binding Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Cell Motility Regulation Of Locomotion Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Synaptic Vesicle Clustering Hemangioblast Cell Differentiation SUMO Conjugating Enzyme Activity Xenobiotic Transport Across Blood-nerve Barrier Regulation Of Cell Population Proliferation Protein Domain Specific Binding Chromatin Binding Regulation Of RNA Metabolic Process Nucleus Regulation Of Cell Development Cellular Developmental Process Animal Organ Regeneration Response To Vitamin B2 Multicellular Organismal-level Homeostasis C/EBP Complex Identical Protein Binding Positive Regulation Of Anion Channel Activity Cell Junction Organization Negative Regulation Of Cell-substrate Adhesion Membrane Assembly Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Basophil Differentiation Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Response To Butyrate
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