DRG1 and STK16

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		DRG1	STK16
Description		developmentally regulated GTP binding protein 1	serine/threonine kinase 16
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Body	Nucleoplasm Cytoplasm Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane Nuclear Body Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Hydrolase Activity Potassium Ion Binding Identical Protein Binding Metal Ion Binding	Nucleotide Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Cytoplasmic Translation Positive Regulation Of Microtubule Polymerization Regulation Of Mitotic Spindle Assembly	Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus
Pathways		Protein hydroxylation
Drugs			Fostamatinib
Diseases
GWAS		Fish- and plant-related diet ( 32066663) Neutrophil count ( 27863252 32888494) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Sum basophil neutrophil counts ( 27863252) Thyroid stimulating hormone levels ( 32769997)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		19 interacting genes: CAPNS1 CEBPA CFTR CLDN1 COIL LNX1 LYL1 MEOX2 NF2 PHC2 PTEN RWDD1 SKIL SRPK2 SSX2IP STK16 TAL1 UBE2I ZC3H15	85 interacting genes: ADAMTSL4 AGR2 ARNT2 ATP23 BHLHA9 CALCOCO2 CBX3 CCDC33 CFP CRX CSKMT CSNK2B CYSRT1 DDIT4L DNAJA3 DRG1 EFEMP2 EFHC2 ELK1 FLACC1 FRS3 FXR1 GABPA IKZF3 INCA1 KCTD14 KCTD17 KLHL20 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-1 KRTAP13-2 KRTAP26-1 KRTAP6-3 MBP MEOX2 MGAT5B MIER3 MIIP MTUS2 NAA80 NAGK NBPF19 NIF3L1 NOTCH2NLA PCSK5 PKNOX2 PLA2G10 PLSCR1 PLSCR3 PRDM6 PRKAR1B PTH1R REL RFX6 RPIA RSPO4 SAXO1 SKIL SOCS2 SPRY2 SSC4D TCF12 TCF4 TLE5 TNFAIP1 TRAF3IP2 TRIM27 TRIM42 TRIP6 TUBA4A USP54 YPEL3 ZMAT1 ZNF330 ZNF343 ZNF774
Entrez ID		4733	8576
HPRD ID		16034	05281
Ensembl ID		ENSG00000185721	ENSG00000115661
Uniprot IDs		Q9Y295	B4DPS1 B8ZZI5 O75716
PDB IDs		2EKI	2BUJ
Enriched GO Terms of Interacting Partners?		Developmental Maturation Response To Ketone Protein-containing Complex PDZ Domain Binding Definitive Hemopoiesis Lens Fiber Cell Differentiation Synapse Maturation Anatomical Structure Formation Involved In Morphogenesis PML Body Granulocyte Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Response To Dexamethasone Regulation Of Cell Cycle Cell Maturation Enzyme Binding 14-3-3 Protein Binding Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Cell Motility Regulation Of Locomotion Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Synaptic Vesicle Clustering Hemangioblast Cell Differentiation SUMO Conjugating Enzyme Activity Xenobiotic Transport Across Blood-nerve Barrier Regulation Of Cell Population Proliferation Protein Domain Specific Binding Chromatin Binding Regulation Of RNA Metabolic Process Nucleus Regulation Of Cell Development Cellular Developmental Process Animal Organ Regeneration Response To Vitamin B2 Multicellular Organismal-level Homeostasis C/EBP Complex Identical Protein Binding Positive Regulation Of Anion Channel Activity Cell Junction Organization Negative Regulation Of Cell-substrate Adhesion Membrane Assembly Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Basophil Differentiation Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Response To Butyrate	Keratin Filament Intermediate Filament DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Lead Ion Binding Response To Peptide Response To Cytokine Identical Protein Binding Mercury Ion Binding PML Body
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