MED29 and NRDE2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MED29	NRDE2
Description		mediator complex subunit 29	NRDE-2, necessary for RNA interference, domain containing
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mediator Complex Core Mediator Complex	Nucleus Nucleoplasm Nucleolus Nuclear Speck
	Molecular Function	Transcription Coregulator Activity Protein Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	Mitotic Cell Cycle MRNA Processing DNA Damage Response RNA Splicing Regulatory NcRNA-mediated Heterochromatin Formation Positive Regulation Of RNA Export From Nucleus MRNA Stabilization Cell Division Negative Regulation Of RNA Catabolic Process
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions
Drugs
Diseases
GWAS			Lifespan ( 25918517) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		11 interacting genes: ABI2 ABI3 BCAS2 CEBPA EIF2B1 MED14 MED20 MED9 NRDE2 SSC5D USP47	11 interacting genes: ARFIP2 CCDC183 HAUS8 ITGB3BP LHX3 MED29 MESD RCOR3 SPG21 UQCC2 VPS28
Entrez ID		55588	55051
HPRD ID		13748	12625
Ensembl ID		ENSG00000063322	ENSG00000119720
Uniprot IDs		B4DUA7 Q9NX70	Q9H7Z3
PDB IDs		7EMF 7ENA 7ENC 7ENJ 7LBM 8GXQ 8GXS 8T9D 8TQW 8TRH	6IEH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation Core Mediator Complex Mediator Complex RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II Transcription Preinitiation Complex Assembly Actin-based Cell Projection Regulation Of Transcription Initiation By RNA Polymerase II SCAR Complex Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation Transcription Coregulator Activity Protein-DNA Complex Assembly Regulation Of Lamellipodium Assembly Regulation Of Dendritic Spine Morphogenesis Regulation Of Lamellipodium Organization Peptidyl-tyrosine Phosphorylation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Signaling Adaptor Activity Zonula Adherens Assembly Kinase Binding CHOP-C/EBP Complex White Fat Cell Proliferation Detection Of Bacterial Lipoprotein
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