NRDE2 and MED29

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NRDE2	MED29
Description		NRDE-2, necessary for RNA interference, domain containing	mediator complex subunit 29
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Speck	Nucleus Nucleoplasm Mediator Complex Core Mediator Complex
	Molecular Function	Protein Binding	Transcription Coregulator Activity Protein Binding
	Biological Process	Mitotic Cell Cycle MRNA Processing DNA Damage Response RNA Splicing Regulatory NcRNA-mediated Heterochromatin Formation Positive Regulation Of RNA Export From Nucleus MRNA Stabilization Cell Division Negative Regulation Of RNA Catabolic Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways			PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions
Drugs
Diseases
GWAS		Lifespan ( 25918517) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		11 interacting genes: ARFIP2 CCDC183 HAUS8 ITGB3BP LHX3 MED29 MESD RCOR3 SPG21 UQCC2 VPS28	11 interacting genes: ABI2 ABI3 BCAS2 CEBPA EIF2B1 MED14 MED20 MED9 NRDE2 SSC5D USP47
Entrez ID		55051	55588
HPRD ID		12625	13748
Ensembl ID		ENSG00000119720	ENSG00000063322
Uniprot IDs		Q9H7Z3	B4DUA7 Q9NX70
PDB IDs		6IEH	7EMF 7ENA 7ENC 7ENJ 7LBM 8GXQ 8GXS 8T9D 8TQW 8TRH
Enriched GO Terms of Interacting Partners?			Positive Regulation Of DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation Core Mediator Complex Mediator Complex RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II Transcription Preinitiation Complex Assembly Actin-based Cell Projection Regulation Of Transcription Initiation By RNA Polymerase II SCAR Complex Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation Transcription Coregulator Activity Protein-DNA Complex Assembly Regulation Of Lamellipodium Assembly Regulation Of Dendritic Spine Morphogenesis Regulation Of Lamellipodium Organization Peptidyl-tyrosine Phosphorylation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Signaling Adaptor Activity Zonula Adherens Assembly Kinase Binding CHOP-C/EBP Complex White Fat Cell Proliferation Detection Of Bacterial Lipoprotein
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