DDX19A and MIF4GD

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		DDX19A	MIF4GD
Description		DEAD-box helicase 19A	MIF4G domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Membrane	Nucleus Nucleolus Cytoplasm Golgi Apparatus Cytosol Histone MRNA Stem-loop Binding Complex
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity	RNA Binding Protein Binding Translation Activator Activity Identical Protein Binding
	Biological Process	Response To Zinc Ion Poly(A)+ MRNA Export From Nucleus Positive Regulation Of Apoptotic Process	Cap-dependent Translational Initiation Regulation Of Translation Regulation Of Translational Initiation Positive Regulation Of Translation
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Branched-chain amino acid levels (Isoleucine) ( 27898682) Branched-chain amino acid levels (Valine) ( 27898682) Malaria ( 31844061)
Interacting Genes		5 interacting genes: CFTR LIG4 MDFI MIF4GD NME1	21 interacting genes: AQP1 ATPAF2 CFAP206 CHCHD2 CRYBA4 DDIAS DDX19A EIF3G ENKD1 EXOSC6 FAM110A HDAC4 HGS HINFP MKRN3 NTAQ1 PDE4DIP PPARG SMARCB1 SVIL UBQLN4
Entrez ID		55308	57409
HPRD ID		07732	10629
Ensembl ID		ENSG00000168872	ENSG00000125457
Uniprot IDs		B4DS24 I3L0H8 Q9NUU7	A0A0S2Z5K9 A0A0S2Z5S7 A0A0S2Z5T5 A9UHW6 J3KSB8 J3QLJ5
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency DNA Ligase Activity DN2 Thymocyte Differentiation Acetyl-CoA Catabolic Process Acetyl-CoA Binding Coenzyme A Binding ITP Biosynthetic Process Farnesyl Diphosphate Kinase Activity Protein Histidine Kinase Activity ITP Metabolic Process Succinyl-CoA Binding Histone MRNA Stem-loop Binding Complex Transepithelial Water Transport Magnesium Ion Binding Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization DNA-dependent Protein Kinase-DNA Ligase 4 Complex Immunoglobulin V(D)J Recombination Nonhomologous End Joining Complex Nucleotide-excision Repair, DNA Gap Filling Phosphotransferase Activity, Phosphate Group As Acceptor UTP Biosynthetic Process DNA Nuclease Activity Cap-dependent Translational Initiation Regulation Of Body Fluid Levels Amelogenesis GTP Biosynthetic Process UTP Metabolic Process ATPase-coupled Inorganic Anion Transmembrane Transporter Activity 3'-5'-DNA Exonuclease Activity Protein Hexamerization Early Endosome Cellular Developmental Process Double-strand Break Repair Via Classical Nonhomologous End Joining
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