MIF4GD and ATPAF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MIF4GD	ATPAF2
Description		MIF4G domain containing	ATP synthase mitochondrial F1 complex assembly factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Golgi Apparatus Cytosol Histone MRNA Stem-loop Binding Complex	Mitochondrion Mitochondrial Inner Membrane Cytosol Membrane Nuclear Speck
	Molecular Function	RNA Binding Protein Binding Translation Activator Activity Identical Protein Binding	Protein Binding
	Biological Process	Cap-dependent Translational Initiation Regulation Of Translation Regulation Of Translational Initiation Positive Regulation Of Translation	Mitochondrial Proton-transporting ATP Synthase Complex Assembly Proton-transporting ATP Synthase Complex Assembly
Pathways
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 25056061 28991256 29483656) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		21 interacting genes: AQP1 ATPAF2 CFAP206 CHCHD2 CRYBA4 DDIAS DDX19A EIF3G ENKD1 EXOSC6 FAM110A HDAC4 HGS HINFP MKRN3 NTAQ1 PDE4DIP PPARG SMARCB1 SVIL UBQLN4	73 interacting genes: AKAP8L APP ATP5F1A ATP5F1B BEGAIN CDC14A CDK2AP1 CEP57 CFAP206 CFAP68 CIMIP2B CRTC2 CTIF CYSRT1 DDIT3 DLGAP4 EBF1 EBF3 EIF4G1 EWSR1 FCHSD2 FNTB GOLGA6L9 IKZF3 INCA1 KRT34 KRT40 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-2 KRTAP6-3 LGALS9B LNX1 LRRFIP2 LURAP1L LZTS2 MAGEA6 MEDAG MIF4GD NME4 PAK5 PKP4 POLR2J3 POLR3F POLR3H PPP1R16B PRDM14 PRDM6 RAD54B RBM48 RCN1 REL RPH3AL RPIA SAXO4 SORBS2 SPATC1L TCHP TERT TFIP11 TP53BP2 TRIM23 TRIM27 UBAP2 VWC2 WASHC1 ZFP90 ZNF19 ZNF23 ZNF35 ZNF426 ZNF655
Entrez ID		57409	91647
HPRD ID		10629	10599
Ensembl ID		ENSG00000125457	ENSG00000171953
Uniprot IDs		A0A0S2Z5K9 A0A0S2Z5S7 A0A0S2Z5T5 A9UHW6 J3KSB8 J3QLJ5	Q8N5M1
PDB IDs
Enriched GO Terms of Interacting Partners?			Protein Binding Intermediate Filament
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