VRTN and RAB3D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VRTN	RAB3D
Description		vertebrae development associated	RAB3D, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Endosome Cytoplasmic Microtubule Plasma Membrane Synaptic Vesicle Membrane Secretory Granule Azurophil Granule Membrane Zymogen Granule Extracellular Exosome Secretory Vesicle
	Molecular Function	DNA Binding Protein Binding Sequence-specific DNA Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GTP-dependent Protein Binding Myosin V Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Exocytosis Protein Transport Regulation Of Exocytosis Bone Resorption Positive Regulation Of Regulated Secretory Pathway
Pathways			Neutrophil degranulation RAB geranylgeranylation
Drugs
Diseases
GWAS		FEV1 ( 30804560) Lung function (FVC) ( 30804560) Refractive error ( 32231278)	Early cardiac repolarization ( 31600170) HDL cholesterol ( 23505323)
Interacting Genes		10 interacting genes: C9orf72 CTBP2 EIF4A3 FAM90A1 POLR3C RAB2B RAB3A RAB3B RAB3C RAB3D	16 interacting genes: AKT1 AKT2 AP1M2 APP CEP55 CHM CYP2C9 MAST1 RAB3IP RABIF REP15 RIMS2 RNF32 RPH3AL SYTL4 VRTN
Entrez ID		55237	9545
HPRD ID		16593	05070
Ensembl ID		ENSG00000133980	ENSG00000105514
Uniprot IDs		Q9H8Y1	A0A024R7G2 O95716
PDB IDs			2GF9
Enriched GO Terms of Interacting Partners?		Myosin V Binding Regulation Of Exocytosis GTP-dependent Protein Binding Regulation Of Vesicle-mediated Transport Regulation Of Secretion By Cell Regulation Of Secretion GTPase Activity Synaptic Vesicle GTP Binding Exocytosis Positive Regulation Of Exocytosis Vesicle-mediated Transport Endosome Regulation Of Synaptic Vesicle Cycle Secretion By Cell Regulation Of Transport Hydrolase Activity Vesicle Nucleotide Binding Secretion Protein Transport Postsynapse Positive Regulation Of Regulated Secretory Pathway Establishment Of Protein Localization Regulation Of Presynaptic Dense Core Granule Exocytosis Evoked Neurotransmitter Secretion Positive Regulation Of Secretion By Cell Negative Regulation Of Selenocysteine Incorporation Cellular Response To Selenite Ion Positive Regulation Of Secretion Positive Regulation Of Transport Sensory Perception Of Touch Positive Regulation Of Type I Interferon Production Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Regulation Of Dense Core Granule Exocytosis Acrosomal Vesicle Antigen Processing And Presentation Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Secretory Granule Zymogen Granule Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Intracellular Protein Localization Clathrin-sculpted Glutamate Transport Vesicle Membrane Regulation Of Regulated Secretory Pathway Selenocysteine Insertion Sequence Binding Regulation Of Translation At Postsynapse Regulation Of Type I Interferon Production Synaptic Vesicle Membrane Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Acrosomal Vesicle Exocytosis	Establishment Of Protein Localization Protein Transport Vesicle-mediated Transport Intracellular Protein Localization Cellular Localization Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Intracellular Protein Transport Negative Regulation Of Fatty Acid Transport Regulation Of Long-chain Fatty Acid Import Into Cell Peripheral Nervous System Myelin Maintenance Intracellular Transport Negative Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Response To Endoplasmic Reticulum Stress Myelin Maintenance Mammary Gland Epithelial Cell Differentiation Post-Golgi Vesicle-mediated Transport Glycogen Biosynthetic Process Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Vesicle-mediated Transport Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Glycogen Biosynthetic Process Small GTPase Binding Plasma Membrane Organization Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Establishment Of Protein Localization Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Polysaccharide Biosynthetic Process Membrane Organization Regulation Of Generation Of Precursor Metabolites And Energy Molecular Function Activator Activity Establishment Of Localization In Cell Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Transport Positive Regulation Of Small Molecule Metabolic Process Positive Regulation Of Excitatory Postsynaptic Potential Secretion By Cell Regulation Of Fatty Acid Oxidation Endosome Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of D-glucose Import Positive Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Lipid Transport Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Glycogen Metabolic Process Positive Regulation Of Protein Localization Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Exocytosis Positive Regulation Of Transport
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