SAMD4B and RSRC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SAMD4B	RSRC2
Description		sterile alpha motif domain containing 4B	arginine and serine rich coiled-coil 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Binding MRNA Binding Protein Binding Translation Repressor Activity	RNA Binding Protein Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Translation Regulation Of MRNA Stability
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33339817) Obesity-related traits ( 23251661)	Hip circumference adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		8 interacting genes: BCL2L10 CCDC179 CFTR LRRC8E NUTM1 RSRC2 USP53 YWHAG	21 interacting genes: AKAP9 APP CMTM5 CTAG1A CTAG1B GOLGA2 KASH5 NAV1 OGT PFDN5 PNMA1 RINT1 SAMD4B SRPK1 SRPK2 TRIM23 TRIM54 UBQLN1 UBQLN2 UBQLN4 UPF2
Entrez ID		55095	65117
HPRD ID		10960	13342
Ensembl ID		ENSG00000179134	ENSG00000111011
Uniprot IDs		M0QZ22 Q5PRF9 Q66K25 Q8IXP7	Q7L4I2
PDB IDs
Enriched GO Terms of Interacting Partners?			Cytoplasm Positive Regulation Of Response To Endoplasmic Reticulum Stress Polyubiquitin Modification-dependent Protein Binding Response To Stress Regulation Of Proteolysis Regulation Of Protein Catabolic Process Regulation Of Autophagy Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Identical Protein Binding Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Amyloid Fibril Formation Positive Regulation Of ERAD Pathway Regulation Of Protein Metabolic Process Macromolecule Metabolic Process TRNA Threonylcarbamoyladenosine Metabolic Process Microtubule-based Process Autophagy Regulation Of ERAD Pathway Microtubule Nucleation Positive Regulation Of Viral Genome Replication Amyloid-beta Complex Innate Immune Response Growth Cone Lamellipodium Protein-containing Complex Organization Regulation Of Response To Calcium Ion Amylin Binding Cellular Component Assembly Regulation Of Supramolecular Fiber Organization Positive Regulation Of Toll Signaling Pathway Defense Response RNA Polymerase III Assembly RNA Polymerase I Assembly Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Cellular Component Organization Organelle Assembly Cis-Golgi Network Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Regulation Of Macroautophagy Defense Response To Symbiont Regulation Of Glycolytic Process Defense Response To Other Organism Protein-containing Complex Nucleic Acid Metabolic Process Microtubule Cytoskeleton Organization Positive Regulation Of Protein Catabolic Process
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