SAMD4B and CCDC179

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SAMD4B	CCDC179
Description		sterile alpha motif domain containing 4B	coiled-coil domain containing 179
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Binding MRNA Binding Protein Binding Translation Repressor Activity	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Translation Regulation Of MRNA Stability
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33339817) Obesity-related traits ( 23251661)	Thyroid volume in Hashimoto’s thyroiditis ( 32019955)
Interacting Genes		8 interacting genes: BCL2L10 CCDC179 CFTR LRRC8E NUTM1 RSRC2 USP53 YWHAG	3 interacting genes: PPARA SAMD4B ZNF655
Entrez ID		55095	100500938
HPRD ID		10960
Ensembl ID		ENSG00000179134	ENSG00000255359
Uniprot IDs		M0QZ22 Q5PRF9 Q66K25 Q8IXP7	H3BU77
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Appetite Negative Regulation Of Glycolytic Process Cellular Response To Fructose Stimulus Negative Regulation Of Cholesterol Storage Regulation Of Response To Food MDM2/MDM4 Family Protein Binding Enamel Mineralization Response To Fructose DNA-binding Transcription Activator Activity Negative Regulation Of ATP Metabolic Process Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Hepatocyte Apoptotic Process Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Gluconeogenesis Regulation Of Transformation Of Host Cell By Virus Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cardiac Muscle Tissue Growth Regulation Of Appetite Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of ATP Biosynthetic Process Tooth Mineralization Negative Regulation Of Lipid Storage NFAT Protein Binding Positive Regulation Of Transformation Of Host Cell By Virus Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of ATP Biosynthetic Process Behavioral Response To Nicotine Positive Regulation Of Fatty Acid Beta-oxidation Mitogen-activated Protein Kinase Kinase Kinase Binding Positive Regulation Of Fatty Acid Oxidation Nuclear Steroid Receptor Activity Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Nuclear-transcribed MRNA Poly(A) Tail Shortening Translation Repressor Activity Negative Regulation Of MiRNA Transcription Negative Regulation Of Epithelial Cell Apoptotic Process Positive Regulation Of Lipid Catabolic Process Lipoprotein Metabolic Process Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Fatty Acid Oxidation Reactive Nitrogen Species Metabolic Process Ubiquitin Conjugating Enzyme Binding Regulation Of Response To Nutrient Levels Nitric Oxide Metabolic Process Negative Regulation Of Organ Growth Regulation Of Fatty Acid Transport Lactation Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of ATP Metabolic Process Positive Regulation Of Fatty Acid Metabolic Process
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