PRPF39 and LARP4

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		PRPF39	LARP4
Description		pre-mRNA processing factor 39	La ribonucleoprotein 4
Image		No pdb structure
GO Annotations	Cellular Component	Commitment Complex Nucleus U1 SnRNP U2-type Prespliceosome	Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane Cytosolic Small Ribosomal Subunit
	Molecular Function	Protein Binding Pre-mRNA 5'-splice Site Binding	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) Binding
	Biological Process	MRNA 5'-splice Site Recognition RNA Processing MRNA Processing RNA Splicing	Translation Cytoskeleton Organization Post-transcriptional Regulation Of Gene Expression Regulation Of Cell Morphogenesis Positive Regulation Of Translation
Pathways
Drugs
Diseases
GWAS		Lead levels ( 26025379)	Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic widespread musculoskeletal pain ( 33331911) Pulse pressure ( 30578418)
Interacting Genes		15 interacting genes: ARF6 BANP CEBPA DHX30 DMRTB1 GTSE1 LARP4 MBNL1 PRRC2B QKI RBM22 RNU1-1 SF1 TOLLIP TRNAU1AP	26 interacting genes: APP BCAS2 BHLHE40 CRX EXOSC7 FNDC3B KAT5 KRT72 LENG1 LRRK2 LSM5 PAX5 PAX6 PCM1 PFDN5 POU6F2 PRC1 PRPF39 PRPF6 TGM5 TXNL4A WBP4 YPEL3 YTHDF3 ZC3H7A ZNF830
Entrez ID		55015	113251
HPRD ID		17913	17289
Ensembl ID		ENSG00000185246	ENSG00000161813
Uniprot IDs		Q86UA1	Q6P4E2 Q71RC2 Q8TBL5 Q96J85
PDB IDs			2CQK 3PKN 6I9B
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding Protein Localization To Endosome Cytoplasmic Stress Granule MRNA Cis Splicing, Via Spliceosome RNA Splicing Erythrocyte Apoptotic Process Macrophage Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding MRNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Internal N(7)-methylguanine-containing RNA Reader Activity	Spliceosomal Complex RNA Splicing U2-type Precatalytic Spliceosome MRNA Processing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process U4/U6 X U5 Tri-snRNP Complex Cellular Response To Manganese Ion Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Manganese Ion Nucleus Retina Development In Camera-type Eye Golgi-associated Vesicle Regulation Of Amyloid Fibril Formation Cellular Response To Catecholamine Stimulus Cellular Component Assembly Response To Catecholamine U5 SnRNP Microtubule Cytoskeleton Organization Nucleoplasm Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Central Nervous System Development Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Microtubule-based Process Forebrain-midbrain Boundary Formation Pancreatic A Cell Development RNA Binding Establishment Of Mitotic Spindle Orientation RNA Polymerase III Assembly RNA Polymerase I Assembly Histone H2AK5 Acetyltransferase Activity Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?