TIPIN and TEX11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TIPIN	TEX11
Description		TIMELESS interacting protein	testis expressed 11
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Replication Fork Protection Complex	Condensed Nuclear Chromosome Synaptonemal Complex Central Element Chromosome
	Molecular Function	DNA Binding Protein Binding	Protein Binding
	Biological Process	DNA Replication Checkpoint Signaling DNA Damage Checkpoint Signaling DNA Damage Response Positive Regulation Of Cell Population Proliferation Response To UV Replication Fork Processing Mitotic Intra-S DNA Damage Checkpoint Signaling Regulation Of Nuclear Cell Cycle DNA Replication Replication Fork Arrest Cell Cycle Phase Transition Cell Division	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Apoptotic Process Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiotic Nuclear Division Male Gonad Development Fertilization Ectopic Germ Cell Programmed Cell Death Negative Regulation Of Apoptotic Process Chiasma Assembly Negative Regulation Of Developmental Process Meiotic Cell Cycle Negative Regulation Of Reproductive Process
Pathways		Processing of DNA double-strand break ends
Drugs
Diseases
GWAS		Adult body size ( 32376654) Testicular germ cell tumor ( 28604728 28604732)	Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)
Interacting Genes		5 interacting genes: APP CLSPN GSC2 TEX11 TIMELESS	92 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B BRMS1L CATSPERT CBY2 CCDC198 CCND2 CCND3 CD74 CDKN1A CDKN2D CENPP CEP55 CEP85L CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DMTN DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAAP20 FAM156A FAM161B FAM217A FBF1 GATAD2B GPSM3 GRXCR1 HOXB5 HYI ING3 KANK2 KCTD10 KIAA0408 KIAA1217 KRT6B LIN37 LRCH2 LRRC36 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PDZD11 PEX39 PIAS1 POM121 PPP1R18 PRPSAP2 PTPDC1 QKI REXO1L6P RIBC1 RIBC2 SCAF8 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX6 SNX7 SOX5 SPMIP5 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 USP15 UTP14C VIL1 ZNF414
Entrez ID		54962	56159
HPRD ID		16917	02256
Ensembl ID		ENSG00000075131	ENSG00000120498
Uniprot IDs		B4DRF3 Q9BVW5	Q8IYF3
PDB IDs		7PFO 7PLO 8B9D
Enriched GO Terms of Interacting Partners?		DNA Replication Checkpoint Signaling Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine DNA Binding Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Replication Fork Arrest DNA Metabolic Process Replication Fork Protection Complex Cellular Response To Cisplatin Cellular Response To Bleomycin Gene Conversion Male Meiosis Chromosome Segregation Meiotic Gene Conversion DNA Secondary Structure Binding Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Response To Bleomycin Negative Regulation Of Cell Cycle Phase Transition Response To Cisplatin Chiasma Assembly Axon Choice Point Recognition Regulation Of Cell Cycle Heparan Sulfate Binding Signaling Receptor Activator Activity	Axonemal A Tubule Inner Sheath Protein Binding Cytoskeleton Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility RNA Exonuclease Activity Cilium Movement Involved In Cell Motility Cyclin D2-CDK4 Complex Negative Regulation Of Peptidyl-tyrosine Phosphorylation Motile Cilium Spindle Pole
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