TEX11 and SNX6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TEX11	SNX6
Description		testis expressed 11	sorting nexin 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Synaptonemal Complex Central Element Chromosome	Nucleus Cytoplasm Lysosome Endosome Early Endosome Cytosol Membrane Retromer Complex Retromer, Tubulation Complex Cytoplasmic Vesicle Early Endosome Membrane Tubular Endosome Postsynaptic Early Endosome Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding Lipid Binding Dynactin Binding Type I Transforming Growth Factor Beta Receptor Binding Phosphatidylinositol Binding Protein Homodimerization Activity
	Biological Process	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Apoptotic Process Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiotic Nuclear Division Male Gonad Development Fertilization Ectopic Germ Cell Programmed Cell Death Negative Regulation Of Apoptotic Process Chiasma Assembly Negative Regulation Of Developmental Process Meiotic Cell Cycle Negative Regulation Of Reproductive Process	Intracellular Protein Transport Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Transport Regulation Of Macroautophagy Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Retrograde Transport, Endosome To Golgi Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of DNA-templated Transcription Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Regulation Of Histamine Secretion By Mast Cell Cellular Response To Amyloid-beta
Pathways
Drugs
Diseases
GWAS		Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)	Atrial fibrillation ( 29892015) Celiac disease ( 23936387) Diastolic blood pressure ( 30224653) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		92 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B BRMS1L CATSPERT CBY2 CCDC198 CCND2 CCND3 CD74 CDKN1A CDKN2D CENPP CEP55 CEP85L CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DMTN DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAAP20 FAM156A FAM161B FAM217A FBF1 GATAD2B GPSM3 GRXCR1 HOXB5 HYI ING3 KANK2 KCTD10 KIAA0408 KIAA1217 KRT6B LIN37 LRCH2 LRRC36 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PDZD11 PEX39 PIAS1 POM121 PPP1R18 PRPSAP2 PTPDC1 QKI REXO1L6P RIBC1 RIBC2 SCAF8 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX6 SNX7 SOX5 SPMIP5 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 USP15 UTP14C VIL1 ZNF414	30 interacting genes: ACVR2B ACVRL1 BMPR1B BRCA1 BRMS1 CALM1 COIL CSNK2A2 CUL3 DISC1 EGFR ESR1 INSR ITSN1 LEPR NDEL1 NRP1 OGT OPTN PDGFRA PIM1 RAG1 SNX1 SNX2 SNX4 TEX11 TGFBR1 TGFBR2 TNIK TPT1
Entrez ID		56159	58533
HPRD ID		02256	12086
Ensembl ID		ENSG00000120498	ENSG00000129515
Uniprot IDs		Q8IYF3	A0A0A0MRI2 Q9UNH7
PDB IDs
Enriched GO Terms of Interacting Partners?		Axonemal A Tubule Inner Sheath Protein Binding Cytoskeleton Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility RNA Exonuclease Activity Cilium Movement Involved In Cell Motility Cyclin D2-CDK4 Complex Negative Regulation Of Peptidyl-tyrosine Phosphorylation Motile Cilium Spindle Pole	Transmembrane Receptor Protein Serine/threonine Kinase Activity Regulation Of Cell Communication Regulation Of Signal Transduction Receptor Complex Regulation Of Signaling Regulation Of Developmental Process Protein Kinase Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Multicellular Organismal Process Activin Binding Kinase Activity Anatomical Structure Morphogenesis Regulation Of Intracellular Signal Transduction Retina Vasculature Development In Camera-type Eye Positive Regulation Of Developmental Process Positive Regulation Of Signal Transduction Developmental Process Positive Regulation Of Cell Population Proliferation Leptin Receptor Binding Cellular Response To Growth Factor Stimulus Positive Regulation Of Multicellular Organismal Process Animal Organ Development Cell Surface Receptor Signaling Pathway Signal Transduction Transforming Growth Factor Beta Receptor Activity, Type I Response To Growth Factor Enzyme-linked Receptor Protein Signaling Pathway Activin Receptor Complex Activin Receptor Activity, Type I Animal Organ Morphogenesis Activin Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Activity Protein Serine/threonine Kinase Activity Transferase Activity Multicellular Organism Development Protein-containing Complex Regulation Of Programmed Cell Death System Development Transferrin Receptor Binding Negative Regulation Of Apoptotic Process Regulation Of Cell Population Proliferation SMAD Binding Negative Regulation Of Programmed Cell Death Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Regulation Of Apoptotic Process Vasculature Development Identical Protein Binding
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