SYTL2 and MTERF1

Number of citations of the paper that reports this interaction (PubMedID 20195357)
57

Data Source:
BioGRID (pull down)

		SYTL2	MTERF1
Description		synaptotagmin like 2	mitochondrial transcription termination factor 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle Melanosome Exocytic Vesicle	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatase Binding Small GTPase Binding Neurexin Family Protein Binding	Nucleic Acid Binding DNA Binding Double-stranded DNA Binding RNA Binding Protein Binding
	Biological Process	Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Vesicle-mediated Transport	DNA-templated Transcription Termination Termination Of Mitochondrial Transcription DNA Geometric Change
Pathways		Regulation of MITF-M-dependent genes involved in pigmentation	Mitochondrial transcription termination Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS		Pallidum volume ( 31530798) Refractive error ( 32231278)	Blond vs. brown/black hair color ( 30531825) Hemoglobin levels ( 32327693)
Interacting Genes		9 interacting genes: FBXO25 LNX1 MORN4 MTERF1 NRXN1 PPP1CA RAB27A RAB27B YIF1A	7 interacting genes: DCTN1 DNAJC21 EXOC6B SET SGCE SYTL2 TMEM128
Entrez ID		54843	7978
HPRD ID		10260	08373
Ensembl ID		ENSG00000137501	ENSG00000127989
Uniprot IDs		A0A0U1RR07 A0A8J9FM55 Q9HCH5	B4DPR9 Q99551
PDB IDs		3BC1 7OPP 7OPQ 7OPR 8P3G 8P3H 8P3I 8P3J 8P3K	3MVA 3MVB 3N6S 3N7Q 5CKY 5CO0 5CRJ 5CRK
Enriched GO Terms of Interacting Partners?		Myosin V Binding Multivesicular Body Membrane Exocytic Vesicle Multivesicular Body Sorting Pathway Cytotoxic T Cell Degranulation Positive Regulation Of Constitutive Secretory Pathway Protein Localization To Synapse Positive Regulation Of Presynaptic Active Zone Assembly Positive Regulation Of Presynapse Assembly Positive Regulation Of CAMP-mediated Signaling Protein-containing Complex Assembly Involved In Synapse Maturation G Protein Activity RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Secretion By Cell GDP Binding Positive Regulation Of Exocytosis Protein Localization To Cell Junction Termination Of Mitochondrial Transcription Protein Complex Involved In Cell-cell Adhesion Guanylate Kinase-associated Protein Clustering Melanosome Secretory Granule Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Complement-dependent Cytotoxicity Positive Regulation Of Neuromuscular Synaptic Transmission Neuroligin Clustering Involved In Postsynaptic Membrane Assembly Vesicle Localization Positive Regulation Of Termination Of DNA-templated Transcription Positive Regulation Of Termination Of RNA Polymerase II Transcription Exosomal Secretion Secretion Negative Regulation Of Filopodium Assembly Glycogen Granule Late Endosome Establishment Of Protein Localization Weibel-Palade Body Platelet Dense Granule Membrane Cerebellar Granule Cell Differentiation Postsynaptic Density Protein 95 Clustering Neuronal Signal Transduction NMDA Selective Glutamate Receptor Signaling Pathway NMDA Glutamate Receptor Clustering Gamma-aminobutyric Acid Receptor Clustering Trans-synaptic Protein Complex Gephyrin Clustering Involved In Postsynaptic Density Assembly AMPA Selective Glutamate Receptor Signaling Pathway Neuroligin Family Protein Binding Type 1 Fibroblast Growth Factor Receptor Binding RNA Polymerase II Promoter Clearance Regulation Of Glycogen Catabolic Process	Organelle Localization Vesicle Docking Vesicle Docking Involved In Exocytosis Organelle Localization By Membrane Tethering Membrane Docking Cell Cortex Region Positive Regulation Of Neuromuscular Junction Development
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