MTERF1 and SET

Number of citations of the paper that reports this interaction (PubMedID 20195357)
57

Data Source:
BioGRID (pull down)

		MTERF1	SET
Description		mitochondrial transcription termination factor 1	SET nuclear proto-oncogene
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid	Chromatin Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleic Acid Binding DNA Binding Double-stranded DNA Binding RNA Binding Protein Binding	DNA Binding Chromatin Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity Histone Binding
	Biological Process	DNA-templated Transcription Termination Termination Of Mitochondrial Transcription DNA Geometric Change	DNA Replication Nucleosome Assembly Nucleosome Disassembly Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of DNA-templated Transcription
Pathways		Mitochondrial transcription termination Transcriptional activation of mitochondrial biogenesis	Condensation of Prophase Chromosomes HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Hemoglobin levels ( 32327693)	Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457)
Interacting Genes		7 interacting genes: DCTN1 DNAJC21 EXOC6B SET SGCE SYTL2 TMEM128	69 interacting genes: ANP32A APEX1 APP CALM1 CDCA8 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 ENO1 EP300 ESR1 FAM111B FBXO7 FOS FOXO1 GZMA GZMK H1-1 H2BC1 H3-3A H3-4 H4C14 H4C16 HMGB2 IRF1 JUNB KLF5 KMT2A LGMN MDM2 MEOX2 MTERF1 NEDD8 NME1 NUCB1 NUPR1 PAX6 PIK3CG PPP2CA PPP2R1B PRKAR1A PTEN PTMA RAC1 SDCBP SETBP1 SGO1 SGO2 TAF1A TERF1 TERF2 TERF2IP TEX35 THAP7 TLE5 TREX1 TRIM55 TRIM63 UBE3A UCHL5 XRCC6 ZNF17 ZNF438 ZNF85
Entrez ID		7978	6418
HPRD ID		08373	09023
Ensembl ID		ENSG00000127989	ENSG00000119335
Uniprot IDs		B4DPR9 Q99551	A0A8J8YYJ1 Q01105 Q5VXV3
PDB IDs		3MVA 3MVB 3N6S 3N7Q 5CKY 5CO0 5CRJ 5CRK	2E50 7MTO
Enriched GO Terms of Interacting Partners?		Organelle Localization Vesicle Docking Vesicle Docking Involved In Exocytosis Organelle Localization By Membrane Tethering Membrane Docking Cell Cortex Region Positive Regulation Of Neuromuscular Junction Development	Nucleus DNA Binding Chromosome Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleoplasm Negative Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Chromosome Telomere Organization Chromosome, Telomeric Region Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Chromatin Organization Regulation Of Multicellular Organismal Process Chromatin Remodeling Regulation Of Gene Expression Regulation Of Phosphorus Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Nucleosome Assembly Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of ATP Metabolic Process Double-stranded Telomeric DNA Binding Nuclear Telomere Cap Complex Regulation Of Purine Nucleotide Metabolic Process Nucleosome Organization Regulation Of Developmental Process Protein-DNA Complex Assembly Regulation Of Glycolytic Process Regulation Of Cell Cycle Regulation Of Carbohydrate Catabolic Process Protein-containing Complex Negative Regulation Of RNA Metabolic Process Regulation Of Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Chromatin Regulation Of Programmed Cell Death Protein-DNA Complex Double-stranded DNA Binding Intracellular Signal Transduction Positive Regulation Of Macromolecule Metabolic Process
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