HAUS6 and HAUS8

Number of citations of the paper that reports this interaction (PubMedID 19369198)
29

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

		HAUS6	HAUS8
Description		HAUS augmin like complex subunit 6	HAUS augmin like complex subunit 8
Image
GO Annotations	Cellular Component	Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule HAUS Complex Mitotic Spindle Microtubule	Spindle Pole Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule Nuclear Microtubule HAUS Complex Mitotic Spindle Microtubule
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Microtubule Binding
	Biological Process	Microtubule Cytoskeleton Organization Centrosome Cycle Regulation Of Microtubule Nucleation Spindle Assembly Cell Division	Centrosome Cycle Regulation Of Microtubule Nucleation Spindle Assembly Cell Division
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494) Platelet count ( 32888494) Prostate cancer ( 29892016) Prostate cancer (early onset) ( 29892016) Pulse pressure ( 30224653 30578418) Type 2 diabetes ( 30297969) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)	Mean corpuscular hemoglobin concentration ( 32888494) Mosquito bite size ( 28199695) Selective IgA deficiency ( 27723758) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		3 interacting genes: APP HAUS8 KDM1A	14 interacting genes: APP C1orf216 CCHCR1 DEUP1 HAUS6 HSPB1 NME7 NRDE2 NTAQ1 NUP54 OGT TXN2 USHBP1 ZG16B
Entrez ID		54801	93323
HPRD ID		13302	11318
Ensembl ID		ENSG00000147874	ENSG00000131351
Uniprot IDs		Q7Z4H7	Q9BT25
PDB IDs		7SQK	7SQK
Enriched GO Terms of Interacting Partners?		Neuron Maturation Cellular Response To CAMP Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Response To Purine-containing Compound Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Developmental Maturation Amylin Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Endosome To Plasma Membrane Transport Vesicle Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Nuclear Microtubule Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Protein Demethylase Activity Intermediate-density Lipoprotein Particle Epigenetic Regulation Of Gene Expression Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon MRF Binding Regulation Of Spontaneous Synaptic Transmission Response To Light Stimulus NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Response To Fungicide Guanine Metabolic Process Axon Choice Point Recognition Heparan Sulfate Binding	Amyloid-beta Complex Growth Cone Lamellipodium Cytoskeleton-dependent Intracellular Transport Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Microtubule-based Transport Transport Along Microtubule Amylin Binding Positive Regulation Of Toll Signaling Pathway Microtubule-based Process Negative Regulation Of Protein Kinase C Signaling Spindle Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Microtubule Nucleation Protein-N-terminal Glutamine Amidohydrolase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?