PPBP and MOB3B

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		PPBP	MOB3B
Description		pro-platelet basic protein	MOB kinase activator 3B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Platelet Alpha Granule Lumen Tertiary Granule Lumen	Nucleus Cytoplasm
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding D-glucose Transmembrane Transporter Activity	Protein Binding Protein Kinase Activator Activity Metal Ion Binding
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Killing Of Cells Of Another Organism Defense Response To Bacterium Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide D-glucose Transmembrane Transport	Signal Transduction Regulation Of Hippo Signaling
Pathways		Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation
Drugs		Ethanesulfonic acid Copper
Diseases
GWAS		Metabolite levels ( 22916037)	Adult asthma ( 27611488) Asthma ( 27611488) Delirium ( 29631748) Plasma trimethylamine N-oxide levels ( 28439531) Urinary symptoms in response to radiotherapy in prostate cancer ( 23376709)
Interacting Genes		32 interacting genes: CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCL10 CXCL11 CXCL12 CXCL14 CXCL6 CXCL9 CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4	7 interacting genes: LATS1 LATS2 MAPK14 NT5C2 PPBP ST3GAL3 STK3
Entrez ID		5473	79817
HPRD ID		07171	14728
Ensembl ID		ENSG00000163736	ENSG00000120162
Uniprot IDs		P02775	Q86TA1
PDB IDs		1F9P 1NAP 1TVX
Enriched GO Terms of Interacting Partners?		Chemokine Activity Cell Chemotaxis Leukocyte Chemotaxis Chemokine-mediated Signaling Pathway Chemotaxis Locomotion Antimicrobial Humoral Response Granulocyte Chemotaxis Leukocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Myeloid Leukocyte Migration Granulocyte Migration Humoral Immune Response Cytokine Activity Killing Of Cells Of Another Organism Cell Migration Cytokine-mediated Signaling Pathway Mononuclear Cell Migration Cell Motility Cell Killing CXCR Chemokine Receptor Binding Inflammatory Response Eosinophil Chemotaxis Defense Response To Symbiont Eosinophil Migration Defense Response Defense Response To Other Organism Immune System Process Neutrophil Chemotaxis Immune Response CCR Chemokine Receptor Binding Chemokine Receptor Binding Neutrophil Migration Response To External Biotic Stimulus Response To Other Organism Cell-cell Signaling G Protein-coupled Receptor Signaling Pathway Signaling Cell Communication T Cell Chemotaxis Dendritic Cell Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling CXCR3 Chemokine Receptor Binding Dendritic Cell Migration Lymphocyte Chemotaxis Neutrophil Activation Negative Regulation Of Cellular Extravasation T Cell Migration Positive Regulation Of T Cell Migration Extracellular Space	Regulation Of Hippo Signaling Regulation Of Organ Growth Positive Regulation Of Hippo Signaling Negative Regulation Of Canonical Wnt Signaling Pathway Hippo Signaling Negative Regulation Of Wnt Signaling Pathway Inner Cell Mass Cell Fate Commitment Inner Cell Mass Cellular Morphogenesis Regulation Of Canonical Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway Regulation Of Developmental Growth Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Serine Kinase Activity Transferase Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity Protein Serine/threonine Kinase Activity Regulation Of Protein Localization To Nucleus Protein Kinase Activity Spindle Pole Cell Morphogenesis Regulation Of Growth D-glucose Transmembrane Transport Kinase Activity ATP Binding Hexose Transmembrane Transport Canonical Inflammasome Complex Assembly Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of NLRP3 Inflammasome Complex Assembly Protein Metabolic Process Carbohydrate Transmembrane Transport Protein Modification Process Carbohydrate Transport Negative Regulation Of Protein Localization To Nucleus Regulation Of NLRP3 Inflammasome Complex Assembly Nucleotide Binding Protein Phosphorylation Negative Regulation Of Cell Cycle Keratinocyte Differentiation Positive Regulation Of Fat Cell Differentiation Phosphorylation Negative Regulation Of Protein Kinase Activity Nucleoside Phosphotransferase Activity GMP Catabolic Process To Guanine Negative Regulation Of Kinase Activity G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Epidermal Cell Differentiation Canonical Wnt Signaling Pathway Negative Regulation Of Protein Phosphorylation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?