RRN3 and TAF1A

Number of citations of the paper that reports this interaction (PubMedID 11250903)
41

Data Source:
BioGRID (pull down)

		RRN3	TAF1A
Description		RNA polymerase I transcription factor RRN3	TATA-box binding protein associated factor, RNA polymerase I subunit A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	RNA Polymerase I Transcription Regulator Complex Nucleus Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus Microtubule Cytoskeleton
	Molecular Function	RNA Polymerase I Core Binding RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity Protein Binding RNA Polymerase Binding	DNA Binding Protein Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly In Utero Embryonic Development DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase I Promoter Nucleolus Organization Cytoplasm Organization Ribosome Biogenesis Positive Regulation Of DNA-templated Transcription Fibroblast Proliferation Homeostasis Of Number Of Cells Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of DNA-templated Transcription Initiation	Transcription By RNA Polymerase I Transcription By RNA Polymerase II
Pathways		RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape	SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Fruit consumption ( 32066663) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Serum metabolite levels ( 33031748) Triglyceride levels ( 32154731)	Trunk fat mass ( 28552196)
Interacting Genes		10 interacting genes: CCNE1 CDK2 EIF3L MYO1C POLR1A POLR1B PPP2R2A TAF1A TAF1B TAF1C	20 interacting genes: ANP32A ESR1 H2AC20 H2BC21 H3-4 H3C1 H4C1 H4C16 JMJD6 NKAPD1 POLR1G RRN3 RUNX2 SET TAF12 TAF1B TAF1C TBP TP53 UBTF
Entrez ID		54700	9015
HPRD ID		12004	05362
Ensembl ID		ENSG00000085721	ENSG00000143498
Uniprot IDs		B7ZB55 F5H148 Q9NYV6	A8K4K5 B4DS21 Q15573
PDB IDs		7OBA
Enriched GO Terms of Interacting Partners?		Transcription By RNA Polymerase I RNA Polymerase Transcription Factor SL1 Complex DNA-templated Transcription Nucleolus RRNA Transcription Nucleoplasm Cyclin E1-CDK2 Complex RNA Polymerase I Transcription Regulator Complex Nucleolar Large RRNA Transcription By RNA Polymerase I Nucleobase-containing Compound Biosynthetic Process Macromolecule Biosynthetic Process DNA/RNA Hybrid Binding 5'-3' RNA Polymerase Activity RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly RNA Polymerase I Complex Nucleic Acid Metabolic Process RNA Metabolic Process Macromolecule Metabolic Process Fibrillar Center Nucleobase-containing Compound Metabolic Process DNA-directed RNA Polymerase Activity DNA-directed RNA Polymerase Complex Cyclin-dependent Protein Kinase Holoenzyme Complex RRNA Metabolic Process Transcription Preinitiation Complex Assembly RNA Polymerase I Core Factor Complex Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Negative Regulation Of Protein Localization To Nucleolus Nucleologenesis Nucleotidyltransferase Activity Telomere Maintenance Positive Regulation Of Chromatin Organization Cyclin-dependent Protein Kinase Activity Cyclin A2-CDK2 Complex Ribonucleoside Binding X Chromosome Telomere Organization Stereocilium Membrane RNA Polymerase I General Transcription Initiation Factor Activity Viral Translational Termination-reinitiation Mitotic Cell Cycle Phase Transition Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Histone Kinase Activity	Protein-DNA Complex Assembly Protein-containing Complex Assembly RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Transcription Preinitiation Complex Assembly Protein-containing Complex Organization Transcription Initiation At RNA Polymerase I Promoter DNA Binding DNA-templated Transcription Initiation Nucleoplasm Structural Constituent Of Chromatin Chromatin Remodeling Cellular Component Assembly Nucleosome Assembly Protein Heterodimerization Activity Transcription By RNA Polymerase I Nucleosome Nucleosome Organization Chromatin Organization DNA-templated Transcription RNA Polymerase Transcription Factor SL1 Complex RNA Polymerase I General Transcription Initiation Factor Activity Nucleus Macromolecule Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process RNA Metabolic Process Regulation Of DNA-templated Transcription Initiation RRNA Transcription TBP-class Protein Binding Nucleic Acid Metabolic Process RNA Polymerase I Transcription Regulator Complex TFIIB-class Transcription Factor Binding Chromosome Fibroblast Proliferation Protein-containing Complex RNA Polymerase II Preinitiation Complex Assembly Protein Localization To Chromatin Nucleobase-containing Compound Metabolic Process MRNA Transcription Positive Regulation Of Transcription Initiation By RNA Polymerase II Nucleolus Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Chromatin Binding Core Promoter Sequence-specific DNA Binding CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Protein Localization To Chromosome Stem Cell Differentiation
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