TAF1A

Description		TATA-box binding protein associated factor, RNA polymerase I subunit A
Image		No pdb structure
GO Annotations	Cellular Component	RNA Polymerase I Transcription Regulator Complex Nucleus Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus Microtubule Cytoskeleton
	Molecular Function	DNA Binding Protein Binding
	Biological Process	Transcription By RNA Polymerase I Transcription By RNA Polymerase II
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Trunk fat mass ( 28552196)
Novel Interacting Genes		20 novel interacting genes: ANP32A ESR1 H2AC20 H2BC21 H3-4 H3C1 H4C1 H4C16 JMJD6 NKAPD1 POLR1G RRN3 RUNX2 SET TAF12 TAF1B TAF1C TBP TP53 UBTF
Interacting Genes		20 interacting genes: ANP32A ESR1 H2AC20 H2BC21 H3-4 H3C1 H4C1 H4C16 JMJD6 NKAPD1 POLR1G RRN3 RUNX2 SET TAF12 TAF1B TAF1C TBP TP53 UBTF
Entrez ID		9015
HPRD ID		05362
Ensembl ID		ENSG00000143498
Uniprot IDs		A8K4K5 B4DS21 Q15573
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein-DNA Complex Assembly Protein-containing Complex Assembly RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Transcription Preinitiation Complex Assembly Protein-containing Complex Organization Transcription Initiation At RNA Polymerase I Promoter DNA Binding DNA-templated Transcription Initiation Nucleoplasm Structural Constituent Of Chromatin Chromatin Remodeling Cellular Component Assembly Nucleosome Assembly Protein Heterodimerization Activity Transcription By RNA Polymerase I Nucleosome Nucleosome Organization Chromatin Organization DNA-templated Transcription RNA Polymerase Transcription Factor SL1 Complex RNA Polymerase I General Transcription Initiation Factor Activity Nucleus Macromolecule Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process RNA Metabolic Process Regulation Of DNA-templated Transcription Initiation RRNA Transcription TBP-class Protein Binding Nucleic Acid Metabolic Process RNA Polymerase I Transcription Regulator Complex TFIIB-class Transcription Factor Binding Chromosome Fibroblast Proliferation Protein-containing Complex RNA Polymerase II Preinitiation Complex Assembly Protein Localization To Chromatin Nucleobase-containing Compound Metabolic Process MRNA Transcription Positive Regulation Of Transcription Initiation By RNA Polymerase II Nucleolus Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Chromatin Binding Core Promoter Sequence-specific DNA Binding CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Protein Localization To Chromosome Stem Cell Differentiation
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