POU3F3 and POU3F4

Number of citations of the paper that reports this interaction (PubMedID 9105675)
0

Data Source:
HPRD (in vitro)

		POU3F3	POU3F4
Description		POU class 3 homeobox 3	POU class 3 homeobox 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Homodimerization Activity Sequence-specific DNA Binding HMG Box Domain Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Kidney Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Central Nervous System Development Brain Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Negative Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Chemical Homeostasis Urea Transmembrane Transport Metanephric Ascending Thin Limb Development Metanephric Macula Densa Development Metanephric Thick Ascending Limb Development Metanephric Loop Of Henle Development Metanephric DCT Cell Differentiation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Brain Development Sensory Perception Of Sound Cochlea Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process
Pathways		Nephron development
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) General risk tolerance (MTAG) ( 30643258) Response to taxane treatment (docetaxel) ( 23006423) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Chronotype ( 30696823) Heschl's gyrus morphology ( 25130324)
Interacting Genes		5 interacting genes: POU3F4 PPP1R15A SOX10 SOX11 SOX8	5 interacting genes: HNRNPU POU3F1 POU3F2 POU3F3 VPS26C
Entrez ID		5455	5456
HPRD ID		03922	02076
Ensembl ID		ENSG00000198914	ENSG00000196767
Uniprot IDs		P20264	A0A2R8Y739 P49335
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Gliogenesis Sequence-specific Double-stranded DNA Binding Enteric Nervous System Development DNA-binding Transcription Factor Activity Negative Regulation Of Glial Cell Proliferation Oligodendrocyte Development Positive Regulation Of Neurogenesis Peripheral Nervous System Development Positive Regulation Of Nervous System Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Regulation Of Glial Cell Proliferation Negative Regulation Of Gliogenesis Oligodendrocyte Differentiation Morphogenesis Of An Epithelium Regulation Of Neurogenesis Neural Crest Cell Migration Mesenchymal Cell Migration Positive Regulation Of Gliogenesis Positive Regulation Of Gene Expression Glial Cell Development Tissue Morphogenesis Skeletal Muscle Cell Differentiation Positive Regulation Of Cell Development Regulation Of Nervous System Development Animal Organ Development Cis-regulatory Region Sequence-specific DNA Binding Anatomical Structure Morphogenesis Positive Regulation Of Lens Epithelial Cell Proliferation Glial Cell Differentiation Ameboidal-type Cell Migration Negative Regulation Of Cell Differentiation Closure Of Optic Fissure Negative Regulation Of Neurogenesis Negative Regulation Of Nervous System Development Morphogenesis Of A Branching Structure Morphogenesis Of A Branching Epithelium Cell Maturation Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Translational Initiation In Response To Stress Eukaryotic Initiation Factor EIF2 Binding Renal Vesicle Induction DNA Binding Negative Regulation Of Apoptotic Process Regulation Of Cell Development Cell Development DNA-binding Transcription Factor Binding Positive Regulation Of Cell Differentiation Cellular Response To Progesterone Stimulus	Forebrain Ventricular Zone Progenitor Cell Division Sequence-specific DNA Binding Schwann Cell Development Myelination In Peripheral Nervous System Cerebral Cortex Radially Oriented Cell Migration Brain Development Cerebral Cortex Cell Migration RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Telencephalon Cell Migration Forebrain Cell Migration Glial Cell Development Cell Division Inactive Sex Chromosome RNA Localization To Chromatin Myelination Axon Ensheathment Metanephric DCT Cell Differentiation Metanephric Macula Densa Development Sequence-specific Double-stranded DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Poly(C) RNA Binding Positive Regulation Of RNA Metabolic Process Protein Localization To Spindle Microtubule DNA-binding Transcription Factor Activity Neurohypophysis Development Metanephric Thick Ascending Limb Development Metanephric Loop Of Henle Development Epidermis Development Tissue Development TFIIH-class Transcription Factor Complex Binding Dendritic Transport Of Messenger Ribonucleoprotein Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Forebrain Astrocyte Development DNA Binding Metanephric Ascending Thin Limb Development Cell Development Positive Regulation Of Cell Population Proliferation Hypothalamus Cell Differentiation Loop Of Henle Development Cell Differentiation CRD-mediated MRNA Stability Complex Regulation Of Transcription By RNA Polymerase II Transcription Regulator Complex PiRNA Binding RNA Polymerase II C-terminal Domain Binding Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Poly(G) Binding
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