POU3F3

Description		POU class 3 homeobox 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Homodimerization Activity Sequence-specific DNA Binding HMG Box Domain Binding
	Biological Process	Kidney Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Central Nervous System Development Brain Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Negative Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Chemical Homeostasis Urea Transmembrane Transport Metanephric Ascending Thin Limb Development Metanephric Macula Densa Development Metanephric Thick Ascending Limb Development Metanephric Loop Of Henle Development Metanephric DCT Cell Differentiation
Pathways		Nephron development
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) General risk tolerance (MTAG) ( 30643258) Response to taxane treatment (docetaxel) ( 23006423) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Novel Interacting Genes		5 novel interacting genes: POU3F4 PPP1R15A SOX10 SOX11 SOX8
Interacting Genes		5 interacting genes: POU3F4 PPP1R15A SOX10 SOX11 SOX8
Entrez ID		5455
HPRD ID		03922
Ensembl ID		ENSG00000198914
Uniprot IDs		P20264
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Gliogenesis Sequence-specific Double-stranded DNA Binding Enteric Nervous System Development DNA-binding Transcription Factor Activity Negative Regulation Of Glial Cell Proliferation Oligodendrocyte Development Positive Regulation Of Neurogenesis Peripheral Nervous System Development Positive Regulation Of Nervous System Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Regulation Of Glial Cell Proliferation Negative Regulation Of Gliogenesis Oligodendrocyte Differentiation Morphogenesis Of An Epithelium Regulation Of Neurogenesis Neural Crest Cell Migration Mesenchymal Cell Migration Positive Regulation Of Gliogenesis Positive Regulation Of Gene Expression Glial Cell Development Tissue Morphogenesis Skeletal Muscle Cell Differentiation Positive Regulation Of Cell Development Regulation Of Nervous System Development Animal Organ Development Cis-regulatory Region Sequence-specific DNA Binding Anatomical Structure Morphogenesis Positive Regulation Of Lens Epithelial Cell Proliferation Glial Cell Differentiation Ameboidal-type Cell Migration Negative Regulation Of Cell Differentiation Closure Of Optic Fissure Negative Regulation Of Neurogenesis Negative Regulation Of Nervous System Development Morphogenesis Of A Branching Structure Morphogenesis Of A Branching Epithelium Cell Maturation Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Translational Initiation In Response To Stress Eukaryotic Initiation Factor EIF2 Binding Renal Vesicle Induction DNA Binding Negative Regulation Of Apoptotic Process Regulation Of Cell Development Cell Development DNA-binding Transcription Factor Binding Positive Regulation Of Cell Differentiation Cellular Response To Progesterone Stimulus
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