ANLN and FZR1

Number of citations of the paper that reports this interaction (PubMedID 36526897)
63

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ANLN	FZR1
Description		anillin, actin binding protein	fizzy and cell division cycle 20 related 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Actomyosin Contractile Ring Cytosol Cytoskeleton Cell Cortex Actin Cytoskeleton Midbody Bleb Cell Projection	Nucleus Nucleoplasm Anaphase-promoting Complex Cytoplasm Cytosol Nuclear Membrane
	Molecular Function	Actin Binding Protein Binding Cadherin Binding	Protein Binding Anaphase-promoting Complex Binding Ubiquitin-protein Transferase Activator Activity Ubiquitin-like Ligase-substrate Adaptor Activity Ubiquitin Ligase Activator Activity
	Biological Process	Mitotic Cytokinesis Actomyosin Contractile Ring Assembly Septin Ring Assembly Hematopoietic Progenitor Cell Differentiation Regulation Of Exit From Mitosis Septin Ring Organization Cell Division Podocyte Cell Migration Positive Regulation Of Bleb Assembly	DNA Repair DNA Damage Response Mitotic G2 DNA Damage Checkpoint Signaling Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Population Proliferation Protein Ubiquitination Anaphase-promoting Complex-dependent Catabolic Process Regulation Of Meiotic Nuclear Division Thymidine Biosynthetic Process Cell Division Regulation Of Meiotic Cell Cycle Proteolysis Involved In Protein Catabolic Process Lens Fiber Cell Differentiation Protein K11-linked Ubiquitination Positive Regulation Of Ubiquitin Protein Ligase Activity DNA Synthesis Involved In Mitotic DNA Replication Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Negative Regulation Of Cellular Senescence
Pathways		RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle	Autodegradation of Cdh1 by Cdh1:APC/C SCF-beta-TrCP mediated degradation of Emi1 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase Regulation of APC/C activators between G1/S and early anaphase Phosphorylation of Emi1 Senescence-Associated Secretory Phenotype (SASP) Assembly of the pre-replicative complex CDK-mediated phosphorylation and removal of Cdc6 Cyclin A/B1/B2 associated events during G2/M transition Cyclin A:Cdk2-associated events at S phase entry Transcriptional Regulation by VENTX Aberrant regulation of mitotic exit in cancer due to RB1 defects Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Red cell distribution width ( 32888494) Systolic blood pressure ( 26969751)	Red cell distribution width ( 32888494)
Interacting Genes		8 interacting genes: CEBPA CRK FOXP1 FZR1 MARCHF10 SEPTIN7 SUMO2 USP10	95 interacting genes: AKT1S1 ANAPC1 ANAPC11 ANAPC2 ANAPC7 ANLN ARNT BECN1 BEX1 BLID BTRC C7orf25 CCL5 CCNA1 CCNB1 CCND2 CCNE1 CCNF CDC14A CDC27 CDC6 CDK2 CDK4 CDK5 CDK6 CDKN2B CDR2 CDT1 CLSPN CYP17A1 DCPS DKK3 DNAJA1 DNM1L DTYMK E2F3 EPHA2 EPSTI1 ERBB2 FBXO5 FGFR4 GLIS2 GMNN HECW2 HIF1A ID2 KAT2A KIF18B LATS2 MAD2L2 MAK MAP2K3 MAP2K5 MAP3K5 MAPK8 MET MOAP1 MTA3 MYC NAT2 NEDD9 NEK2 NF2 OTUD7B PAX3 PDGFRA PSMC3IP PTP4A3 PTTG1 RASSF1 RB1 RBBP8 SASS6 SENP2 SIRT1 SIRT2 SKIL SKP2 SMURF1 SOX2 SOX4 SRC STK11 TBK1 TEAD2 TERT THRSP TK1 TTF2 UBC UBE2D1 UBE2D3 UBE2K UHRF1 USP10
Entrez ID		54443	51343
HPRD ID		09799	04687
Ensembl ID		ENSG00000011426	ENSG00000105325
Uniprot IDs		A8K5D9 Q9NQW6	Q9UM11
PDB IDs		2Y7B 4XH3 4XOI	4UI9 5L9T 5L9U 8TAR 8TAU 9GAW
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Response To Peptide Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Protein Modification By Small Protein Conjugation Post-translational Protein Modification RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Embryonic Cell Shape Regulation Of Protein Catabolic Process Cellular Response To Tumor Necrosis Factor Cellular Response To Cytokine Stimulus Regulation Of Proteolysis Response To Vitamin B2 C/EBP Complex Helper T Cell Diapedesis Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin Negative Regulation Of Stress Granule Assembly DNA Biosynthetic Process Positive Regulation Of Interleukin-21 Production Kinase Binding Regulation Of Organelle Organization CHOP-C/EBP Complex Response To Tumor Necrosis Factor Cerebellar Neuron Development DNA Synthesis Involved In Mitotic DNA Replication Response To Cytokine Regulation Of Cell Shape Positive Regulation Of Catabolic Process White Fat Cell Proliferation Myeloid Leukocyte Differentiation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Signal Transduction In Response To DNA Damage Protein Ubiquitination Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Thymidine Biosynthetic Process Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Regulation Of Cellular Component Organization Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Response To Phenylpropanoid Diapedesis	Regulation Of Cell Cycle Regulation Of Cell Cycle Process Cell Division Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nucleoplasm G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Nucleus Regulation Of Primary Metabolic Process Cytoplasm Regulation Of Chromosome Segregation Cytosol Regulation Of Chromosome Organization Regulation Of Sister Chromatid Segregation Regulation Of Metabolic Process Regulation Of Protein Modification Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Protein Modification Process Negative Regulation Of Cell Cycle Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Kinase Activity Positive Regulation Of Cell Cycle Phase Transition Spindle Protein Kinase Activity Regulation Of Organelle Organization Negative Regulation Of Metabolic Process Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cell Cycle Process Post-translational Protein Modification Negative Regulation Of Macromolecule Metabolic Process Modification-dependent Protein Catabolic Process Intracellular Signal Transduction Regulation Of Cellular Component Organization Positive Regulation Of Cell Population Proliferation Cellular Response To Stress Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of RNA Metabolic Process Transferase Activity Positive Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?