ANLN and MARCHF10

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ANLN	MARCHF10
Description		anillin, actin binding protein	membrane associated ring-CH-type finger 10
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Actomyosin Contractile Ring Cytosol Cytoskeleton Cell Cortex Actin Cytoskeleton Midbody Bleb Cell Projection
	Molecular Function	Actin Binding Protein Binding Cadherin Binding	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Mitotic Cytokinesis Actomyosin Contractile Ring Assembly Septin Ring Assembly Hematopoietic Progenitor Cell Differentiation Regulation Of Exit From Mitosis Septin Ring Organization Cell Division Podocyte Cell Migration Positive Regulation Of Bleb Assembly	Protein Ubiquitination
Pathways		RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS		Red cell distribution width ( 32888494) Systolic blood pressure ( 26969751)
Interacting Genes		8 interacting genes: CEBPA CRK FOXP1 FZR1 MARCHF10 SEPTIN7 SUMO2 USP10	7 interacting genes: ANLN APP CTBP1 NTAQ1 SRPK2 UBE2H UNC45A
Entrez ID		54443	162333
HPRD ID		09799	08762
Ensembl ID		ENSG00000011426	ENSG00000173838
Uniprot IDs		A8K5D9 Q9NQW6	A0A140VKA1 B3KVK0 G3V1Q5 J3KTN9 Q8NA82
PDB IDs		2Y7B 4XH3 4XOI
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Response To Peptide Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Protein Modification By Small Protein Conjugation Post-translational Protein Modification RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Embryonic Cell Shape Regulation Of Protein Catabolic Process Cellular Response To Tumor Necrosis Factor Cellular Response To Cytokine Stimulus Regulation Of Proteolysis Response To Vitamin B2 C/EBP Complex Helper T Cell Diapedesis Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin Negative Regulation Of Stress Granule Assembly DNA Biosynthetic Process Positive Regulation Of Interleukin-21 Production Kinase Binding Regulation Of Organelle Organization CHOP-C/EBP Complex Response To Tumor Necrosis Factor Cerebellar Neuron Development DNA Synthesis Involved In Mitotic DNA Replication Response To Cytokine Regulation Of Cell Shape Positive Regulation Of Catabolic Process White Fat Cell Proliferation Myeloid Leukocyte Differentiation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Signal Transduction In Response To DNA Damage Protein Ubiquitination Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Thymidine Biosynthetic Process Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Regulation Of Cellular Component Organization Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Response To Phenylpropanoid Diapedesis	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Nucleus Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Cell Cycle Nuclear Speck Organization Positive Regulation Of Bleb Assembly Actomyosin Contractile Ring Septin Ring Assembly Actomyosin Contractile Ring Assembly Septin Ring Organization Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Septin Cytoskeleton Organization Cellular Developmental Process Protein Metabolic Process Protein Modification Process Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Podocyte Cell Migration Heparan Sulfate Binding
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