DCUN1D1 and TRIM39

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		DCUN1D1	TRIM39
Description		defective in cullin neddylation 1 domain containing 1	tripartite motif containing 39
Image
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Protein Ubiquitination Protein Neddylation Regulation Of Protein Neddylation Positive Regulation Of Protein Neddylation	Apoptotic Process Mitotic G2 DNA Damage Checkpoint Signaling Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Protein Stabilization Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Neddylation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Fasting insulin ( 34074324) Parkinson's disease ( 27182965 28011712) Subjective response to lithium treatment ( 26503763)	Anxiety ( 33859377) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Cutaneous lupus erythematosus ( 25827949) Neuroticism ( 29255261)
Interacting Genes		32 interacting genes: ABRAXAS2 ARIH1 ARIH2 ARRDC3 AURKB CALM1 CDIP1 CUL5 DAZAP2 DVL2 FAM168A GMPPA LAPTM5 LZTS2 MAP3K1 NEDD4 PLEKHB2 RHOA RNF11 SMAD2 SUSD6 TLE5 TMEM239 TP53BP2 TRIM39 TRIM54 TRIM8 UBC UBE2D3 UBE2F UBE2M VPS37B	62 interacting genes: APP BTNL2 CACTIN CCNC DCUN1D1 DCX DIP2A EIF4A2 EPHB6 GAMT HINFP KDM1A LMNA LNX1 LXN MED18 MNAT1 MTURN OTUB2 OTUD6A PDLIM5 PLCD4 POLI PRPF3 PSMA6 PSMB1 PSMD9 RAD23A RECK RNF166 SMCO3 TP53 TRIM17 TRIM21 TRIM8 TTC32 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBL5 UBTD1 UBTD2 UBXN1 UBXN6 UBXN7 USP2 USP39 USP5 WDFY3 ZKSCAN4 ZNF26
Entrez ID		54165	56658
HPRD ID		12067	09298
Ensembl ID		ENSG00000043093	ENSG00000204599
Uniprot IDs		B4DM76 C9JVE2 Q96GG9	A0A024RCP5 Q9HCM9
PDB IDs		3TDU 3TDZ 4P5O 5UFI 5V83 5V86 5V88 6B5Q 6BG3 6BG5 6P5V 6P5W 6XOL 6XOM 6XON 6XOO 6XOP 6XOQ 7KWA 8OR2 8OR3	2DID 2DIF 2ECJ
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification Protein Modification By Small Protein Conjugation Protein Modification Process Ubiquitin Protein Ligase Activity Modification-dependent Protein Catabolic Process Intracellular Signal Transduction Protein Ubiquitination Proteolysis Involved In Protein Catabolic Process NEDD8 Conjugating Enzyme Activity Ubiquitin-protein Transferase Activity Ubiquitin-dependent Protein Catabolic Process Ubiquitin Protein Ligase Binding Protein Metabolic Process Midbody NEDD8 Transferase Activity Ubiquitin Ligase Complex Cleavage Furrow Formation Mitotic Spindle Assembly Macromolecule Catabolic Process Protein Targeting To Vacuole Innate Immune Response Negative Regulation Of Signal Transduction Protein Polyubiquitination Transferase Activity Establishment Of Protein Localization To Vacuole Proteolysis Spindle Midzone Assembly Negative Regulation Of Cell Communication Negative Regulation Of Signaling Mitotic Cytokinesis Cytosol Intrinsic Apoptotic Signaling Pathway Vesicle Protein K63-linked Ubiquitination Cul5-RING Ubiquitin Ligase Complex Endosome Defense Response To Symbiont Negative Regulation Of CGAS/STING Signaling Pathway Defense Response To Other Organism Protein Binding Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Signal Transduction Regulation Of Cytokinesis Ubiquitin-like Protein Transferase Activity Spindle Assembly Cytoskeleton-dependent Cytokinesis Mitotic Spindle Organization Protein Localization To Vacuole Protein Neddylation	Ubiquitin Conjugating Enzyme Activity Post-translational Protein Modification Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Polyubiquitination Proteolysis Involved In Protein Catabolic Process Ubiquitin-protein Transferase Activity Protein Metabolic Process Modification-dependent Protein Catabolic Process Proteolysis Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Macromolecule Metabolic Process Protein K48-linked Ubiquitination Macromolecule Catabolic Process Protein Monoubiquitination Protein K11-linked Ubiquitination Protein K63-linked Ubiquitination Catabolic Process Nucleus Protein Binding Nucleoplasm Proteasomal Protein Catabolic Process Ubiquitin Protein Ligase Binding Ubiquitin Binding Regulation Of Post-translational Protein Modification Ubiquitin Ligase Complex Regulation Of Protein Ubiquitination Positive Regulation Of Post-translational Protein Modification Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Regulation Of Protein Modification Process Cysteine-type Deubiquitinase Activity Transferase Activity Protein Deubiquitination Positive Regulation Of Protein Polyubiquitination UBC13-MMS2 Complex Ubiquitin Protein Ligase Activity Positive Regulation Of Protein Ubiquitination Positive Regulation Of Protein Modification Process Protein Modification By Small Protein Removal Regulation Of Protein Metabolic Process Negative Regulation Of Protein Deubiquitination ISG15 Transferase Activity Ubiquitin Conjugating Enzyme Complex DNA Repair Cytosol Protein K6-linked Ubiquitination Protein Autoubiquitination Positive Regulation Of Protein Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?