GINS2 and GINS4

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		GINS2	GINS4
Description		GINS complex subunit 2	GINS complex subunit 4
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GO Annotations	Cellular Component	GINS Complex Nucleus Nucleoplasm Chromosome CMG Complex	GINS Complex Nucleus Nucleoplasm Chromosome Cytoplasm CMG Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Double-strand Break Repair Via Break-induced Replication DNA Replication	Double-strand Break Repair Via Break-induced Replication Inner Cell Mass Cell Proliferation DNA Replication DNA-templated DNA Replication
Pathways		Unwinding of DNA Unwinding of DNA	Unwinding of DNA Unwinding of DNA
Drugs
Diseases
GWAS		Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		1 interacting genes: GINS4	13 interacting genes: - BIN3 CTNNBIP1 DMAP1 GINS2 IDO2 KIF16B LHX8 PBX4 POLA1 POLD1 POLE PPP1R13B
Entrez ID		51659	84296
HPRD ID		15197	11583
Ensembl ID		ENSG00000131153	ENSG00000147536
Uniprot IDs		Q9Y248	Q9BRT9
PDB IDs		2E9X 2EHO 2Q9Q 6XTX 6XTY 7PFO 7PLO 8B9D 8OK2	2E9X 2EHO 2Q9Q 6XTX 6XTY 7PFO 7PLO 8B9D 8OK2
Enriched GO Terms of Interacting Partners?		CMG Complex Double-strand Break Repair Via Break-induced Replication Inner Cell Mass Cell Proliferation GINS Complex DNA-templated DNA Replication Double-strand Break Repair Via Homologous Recombination Recombinational Repair DNA Replication Double-strand Break Repair DNA Recombination	DNA Polymerase Activity DNA-directed DNA Polymerase Activity DNA Replication Proofreading DNA Synthesis Involved In DNA Repair Leading Strand Elongation DNA Replication DNA-templated DNA Replication Nucleotide-excision Repair, DNA Gap Filling DNA Repair DNA Strand Elongation Involved In DNA Replication Nucleotidyltransferase Activity DNA Biosynthetic Process Base-excision Repair, Gap-filling DNA Strand Elongation DNA Metabolic Process DNA Damage Response 4 Iron, 4 Sulfur Cluster Binding Actin Cortical Patch Localization Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Iron-sulfur Cluster Binding Beta-catenin-ICAT Complex Indoleamine 2,3-dioxygenase Activity Lagging Strand Elongation DNA Synthesis Involved In UV-damage Excision Repair Unidimensional Cell Growth Tryptophan 2,3-dioxygenase Activity Mitotic DNA Replication Initiation Nucleobase-containing Compound Biosynthetic Process Alpha DNA Polymerase:primase Complex Error-free Translesion Synthesis Delta DNA Polymerase Complex Epsilon DNA Polymerase Complex Single-stranded DNA 3'-5' DNA Exonuclease Activity GINS Complex Myoblast Migration Involved In Skeletal Muscle Regeneration Response To Ethanol L-tryptophan Catabolic Process To Kynurenine Cellular Response To Stress DNA Replication, Synthesis Of Primer Nucleotide-excision Repair Complex Negative Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Transcription Initiation By RNA Polymerase II
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