NELFCD and FRMD5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		NELFCD	FRMD5
Description		negative elongation factor complex member C/D	FERM domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Membrane NELF Complex	Cytoskeleton Adherens Junction Membrane Anchoring Junction
	Molecular Function	RNA Binding Protein Binding	Integrin Binding Protein Binding Cytoskeletal Protein Binding Protein Kinase Binding
	Biological Process	Negative Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of DNA-templated Transcription	Regulation Of Cell Migration Actomyosin Structure Organization Positive Regulation Of Cell Adhesion Negative Regulation Of Cell Motility
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Mean platelet volume ( 27863252 32888494) Platelet distribution width ( 27863252)	Appendicular lean mass ( 33097823) Hemoglobin levels ( 32327693) Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643) Serum albumin levels ( 23022100) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 28334899) Triglycerides ( 20686565 24097068 25961943) Urinary tract infection frequency ( 28928442) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		22 interacting genes: AAMP AR ARAF ARPC4 CACNA1A CD40 CDSN DNAJA1 ENDOV EPRS1 FRMD5 GSTM4 HDAC11 MTA1 NELFA OGT PRMT5 SERF2 SMAD4 TXK UBE3A ZNF638	3 interacting genes: CEP250 NELFCD SC5D
Entrez ID		51497	84978
HPRD ID		16096	17493
Ensembl ID		ENSG00000101158	ENSG00000171877
Uniprot IDs		H0UI80 Q8IXH7	A0A087WVP2 A8K1U8 B3KVN9 B5MC67 H0YKW6 Q7Z6J6
PDB IDs		5L3X 6GML 7PKS 7YCX 8JJ6 8RBX 8UHA 8UHD 8UHG 8UI0 8UIS 8W8E 9J0N 9J0O 9J0P
Enriched GO Terms of Interacting Partners?		Prostate Gland Growth Regulation Of Protein Ubiquitination Endothelial Cell Activation Circadian Regulation Of Gene Expression Seminiferous Tubule Development Positive Regulation Of RNA Metabolic Process Regulation Of Post-translational Protein Modification Rhythmic Process Cytosol Prostate Induction Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Regulation Of MAPK Cascade Cellular Response To Oxygen-containing Compound Androgen Receptor Signaling Pathway Male Somatic Sex Determination Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Protein Modification Process Regulation Of TOR Signaling Negative Regulation Of Cornification Proline-tRNA Ligase Activity Prolyl-tRNA Aminoacylation Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Sperm Entry Positive Regulation Of Golgi Lumen Acidification Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Circadian Rhythm Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway DNA Endonuclease Activity, Producing 5'-phosphomonoesters Regulation Of Ubiquitin-dependent Protein Catabolic Process Enzyme Binding	Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol C-5 Sterol Desaturase Activity Delta7-sterol 5(6)-desaturase Activity Regulation Of Centriole-centriole Cohesion NELF Complex Positive Regulation Of Protein Localization To Centrosome Regulation Of Ferroptosis Negative Regulation Of Ferroptosis Spindle Pole Centrosome Centriole-centriole Cohesion Regulation Of Protein Localization To Centrosome Detection Of Light Stimulus Involved In Visual Perception Protein Localization To Centrosome Negative Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Transcription Elongation By RNA Polymerase II Cholesterol Biosynthetic Process Sterol Biosynthetic Process Protein Localization To Cytoskeleton Non-motile Cilium Assembly Photoreceptor Inner Segment Detection Of Light Stimulus
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