EVL and BEGAIN

		EVL	BEGAIN
Description		Enah/Vasp-like	brain enriched guanylate kinase associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Membrane Lamellipodium Cell Projection	Cytoplasm Membrane Synapse Postsynapse
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding	Protein Binding
	Biological Process	Actin Filament Organization Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Actin Polymerization Or Depolymerization Animal Organ Morphogenesis Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Cellular Component Biogenesis Protein Homotetramerization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly Regulation Of Actin Filament Organization Negative Regulation Of Ruffle Assembly Positive Regulation Of Supramolecular Fiber Organization	Evoked Excitatory Postsynaptic Potential
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors RHO GTPases Activate Formins	Neurexins and neuroligins
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 25663218)	Chronotype ( 30696823) Menarche (age at onset) ( 21102462) Metabolite levels ( 23823483) Refractive error ( 32231278)
Interacting Genes		46 interacting genes: ABI1 ABI3 ABL1 APBB1 APBB1IP ATG2B BDKRB1 BEGAIN C14orf132 CEBPA CFTR CKB CRKL DNMBP ENAH F11R FXR1 FXR2 FYB1 FYN GSKIP HCK HTT KRT17 KRT34 LRP1B LYN PFN2 POT1 PRPF40A RAD51 SEMA6A SH3RF1 SPTA1 SPTAN1 SRC TCERG1 TERF1 TES TRIM9 WAS WASL XIRP1 ZDHHC17 ZNF655 ZYX	49 interacting genes: ABLIM1 APP AQP1 ATPAF2 BAHD1 BCL11B BMP7 CATSPER1 CDC23 DDX6 DEF6 DLG1 DLG4 DTNB ENKD1 EVL FAM107A FAM161A FAM90A1 GEM GFI1B GMCL1 GUCD1 HDAC4 HGS HID1 KIAA0408 KIFC3 LENG1 MAB21L3 PRPF18 PRR35 QSOX1 RASAL3 RBL1 RIBC2 SAXO1 TRAF4 TRIM27 USP2 ZFP64 ZNF250 ZNF319 ZNF417 ZNF572 ZNF587 ZNF648 ZNF774 ZNF835
Entrez ID		51466	57596
HPRD ID		10942	06459
Ensembl ID		ENSG00000196405	ENSG00000183092
Uniprot IDs		A0A024R6K5 A0A2D1PGY7 Q9UI08	A0A1B0GTT1 G3V3A2 G3V3R5 Q9BUH8
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Cytoskeleton Organization Fc Receptor Mediated Stimulatory Signaling Pathway Actin Filament-based Process Cytoskeleton Actin Filament Organization Fc-gamma Receptor Signaling Pathway Actin Cytoskeleton Organization Supramolecular Fiber Organization Anchoring Junction Non-membrane Spanning Protein Tyrosine Kinase Activity Peptidyl-tyrosine Phosphorylation Fc Receptor Signaling Pathway Cell Migration Cell Motility Actin Polymerization Or Depolymerization Lamellipodium Regulation Of Plasma Membrane Bounded Cell Projection Organization Ephrin Receptor Binding Regulation Of Cell Projection Organization Negative Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Cellular Component Organization Regulation Of Cell Shape Negative Regulation Of Cellular Component Organization Postsynapse Regulation Of Cell Morphogenesis Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Actin Filament Organization Integrin-mediated Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Response To Xenobiotic Stimulus Cell Junction Anatomical Structure Morphogenesis Cell Projection Organization Cytoplasm Cellular Response To Transforming Growth Factor Beta Stimulus Stimulatory C-type Lectin Receptor Signaling Pathway Phospholipase Binding Cellular Response To Lectin Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Protein Tyrosine Kinase Activity Regulation Of Developmental Process Synapse Protein-containing Complex Regulation Of Actin Cytoskeleton Organization Leukocyte Migration Regulation Of Cell Projection Assembly Immune Response-activating Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition Zinc Ion Binding NMDA Selective Glutamate Receptor Signaling Pathway Protein Binding Regulation Of Mitotic Cell Cycle Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?