BEGAIN and PRR35

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BEGAIN	PRR35
Description		brain enriched guanylate kinase associated	proline rich 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane Synapse Postsynapse
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Evoked Excitatory Postsynaptic Potential
Pathways		Neurexins and neuroligins
Drugs
Diseases
GWAS		Chronotype ( 30696823) Menarche (age at onset) ( 21102462) Metabolite levels ( 23823483) Refractive error ( 32231278)	L1-L4 bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		49 interacting genes: ABLIM1 APP AQP1 ATPAF2 BAHD1 BCL11B BMP7 CATSPER1 CDC23 DDX6 DEF6 DLG1 DLG4 DTNB ENKD1 EVL FAM107A FAM161A FAM90A1 GEM GFI1B GMCL1 GUCD1 HDAC4 HGS HID1 KIAA0408 KIFC3 LENG1 MAB21L3 PRPF18 PRR35 QSOX1 RASAL3 RBL1 RIBC2 SAXO1 TRAF4 TRIM27 USP2 ZFP64 ZNF250 ZNF319 ZNF417 ZNF572 ZNF587 ZNF648 ZNF774 ZNF835	80 interacting genes: ABHD11 ACTMAP ACY1 APPL2 ARMC5 ASB15 BEGAIN BIRC7 BPIFA1 CARD10 CCDC136 CFAP68 CNOT2 CRX CYSRT1 EXOC8 FAM168B FHL3 FRYL GIGYF1 GRAP2 HOMER3 HOOK2 HPCA HSPB2 HSPB2-C11orf52 INSC INTS11 JUP KLHL26 KRT31 KRT34 KRT35 KRTAP10-7 KRTAP12-1 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LASP1 LONRF1 LZTS2 MAGED1 MCCD1 MKRN3 MSS51 MTUS2 N4BP3 NBPF19 NOTCH2NLA OIP5 OXER1 PFDN5 PLAGL2 PPIL1 PPP1R13B PRR20A PRR20B PRR20C PRR20D PRR20E PSTPIP1 RBPMS RNF144B RUSC1 SMUG1 SPAG8 TBX19 TLE5 TRIM27 TRIM54 TRIM73 TTC19 TTLL12 UBASH3B UBXN11 USP54 ZMYND12 ZNF655
Entrez ID		57596	146325
HPRD ID		06459	10046
Ensembl ID		ENSG00000183092	ENSG00000161992
Uniprot IDs		A0A1B0GTT1 G3V3A2 G3V3R5 Q9BUH8	P0CG20
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition Zinc Ion Binding NMDA Selective Glutamate Receptor Signaling Pathway Protein Binding Regulation Of Mitotic Cell Cycle Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process	Intermediate Filament Keratin Filament
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