UBE2J1 and LY6G6C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UBE2J1	LY6G6C
Description		ubiquitin conjugating enzyme E2 J1	lymphocyte antigen 6 family member G6C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase Complex Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Membrane Protein-containing Complex Side Of Membrane
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding Identical Protein Binding
	Biological Process	Protein Polyubiquitination Spermatid Development Regulation Of Macrophage Cytokine Production Protein Ubiquitination Protein N-linked Glycosylation Via Asparagine Regulation Of Tumor Necrosis Factor Production ERAD Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS			Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Smoking initiation (ever regular vs never regular) ( 30679032) Ulcerative colitis ( 28067908)
Interacting Genes		50 interacting genes: AQP2 AQP6 BIRC2 BRCA1 CD79A CDS1 CLTRN CREB3 CYB561 DIO2 EBP ELOVL4 FAM209A FAM210B FCER1G GKN1 GOLT1A JAGN1 LAPTM5 LRSAM1 LY6G6C LYVE1 MAPKAPK2 MS4A6E PJA2 PLPPR2 PRKN PROKR2 REEP4 RNF2 SEC11C SLC10A6 SLC26A5 SLC33A2 SLC71A2 SYVN1 TLCD4 TM4SF18 TM4SF19 TMEM14B TMEM31 TMEM51 TMX2 TOPORS TRHR TRIM27 TRIM63 UBA1 UBC UBR5	8 interacting genes: ARLN SLC38A7 SLC39A2 SLC41A2 TMEM203 UBE2J1 YIPF6 ZDHHC17
Entrez ID		51465	80740
HPRD ID		15599	14329
Ensembl ID		ENSG00000198833	ENSG00000204421
Uniprot IDs		Q9Y385	A0A1U9X7Z1 O95867
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Ubiquitin-protein Transferase Activity Ubiquitin Protein Ligase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Polyubiquitination Endoplasmic Reticulum Membrane Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Endoplasmic Reticulum Protein Binding Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Modification-dependent Protein Catabolic Process Renal Water Transport Protein K48-linked Ubiquitination Transferase Activity Ubiquitin Ligase Complex Negative Regulation Of Response To Endoplasmic Reticulum Stress Protein K29-linked Ubiquitination Protein Modification Process	Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Membrane L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity Nickel Cation Transport Asparagine Transport L-asparagine Transmembrane Transporter Activity Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity Monoatomic Cation Transport Cadmium Ion Transmembrane Transport Metal Ion Transport Endoplasmic Reticulum Hrd1p Ubiquitin Ligase Complex Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Glutamine Transport L-glutamine Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity Cobalt Ion Transport Golgi Trans Cisterna Golgi Medial Cisterna Negative Regulation Of Protein Exit From Endoplasmic Reticulum Intestinal Epithelial Cell Development Regulation Of Neurotrophin TRK Receptor Signaling Pathway Manganese Ion Transport Regulation Of Retrograde Protein Transport, ER To Cytosol Golgi-associated Vesicle Membrane Monoatomic Ion Transport Magnesium Ion Transmembrane Transporter Activity Columnar/cuboidal Epithelial Cell Development Lipoprotein Transport Magnesium Ion Transport Magnesium Ion Transmembrane Transport Monoatomic Cation Transmembrane Transporter Activity
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