RHCG and C1QL4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RHCG	C1QL4
Description		Rh family C glycoprotein	complement C1q like 4
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome	Extracellular Region Collagen Trimer Extracellular Space
	Molecular Function	Protein Binding Ammonium Channel Activity Ankyrin Binding Carbon Dioxide Transmembrane Transporter Activity Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Intracellular Monoatomic Ion Homeostasis Regulation Of PH Amine Transport Epithelial Cell Differentiation Carbon Dioxide Transmembrane Transport Homeostatic Process Transepithelial Ammonium Transport Ammonium Transmembrane Transport Ammonium Homeostasis	Negative Regulation Of Fat Cell Differentiation Fibroblast Proliferation Negative Regulation Of Fibroblast Proliferation ERK1 And ERK2 Cascade Negative Regulation Of ERK1 And ERK2 Cascade
Pathways		Rhesus glycoproteins mediate ammonium transport
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Dentures ( 31235808) Femur bone mineral density x serum urate levels interaction ( 34046847) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
Interacting Genes		13 interacting genes: ARLN C1QL4 CXCL9 ERMP1 FXYD6 GPR25 IGFBP5 MS4A13 TMEM60 TMEM97 TRARG1 UPK1B YIPF6	19 interacting genes: CD53 CERS4 FATE1 FNDC9 GOLM1 GPR152 IL10RA LEUTX MFF RHCG SCARA5 SGTA SGTB SLC38A1 SSMEM1 TMEM179B TMPRSS2 TRHR UBQLN2
Entrez ID		51458	338761
HPRD ID		16102	17350
Ensembl ID		ENSG00000140519	ENSG00000186897
Uniprot IDs		Q9UBD6	A0A3B0INP7 Q86Z23
PDB IDs		3HD6
Enriched GO Terms of Interacting Partners?			Membrane TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of ERAD Pathway Identical Protein Binding Regulation Of ERAD Pathway Establishment Of Protein Localization To Organelle Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Interleukin-10 Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Thyrotropin-releasing Hormone Receptor Activity Ferritin Receptor Activity Protein Targeting
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