C1QL4 and RHCG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C1QL4	RHCG
Description		complement C1q like 4	Rh family C glycoprotein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Ammonium Channel Activity Ankyrin Binding Carbon Dioxide Transmembrane Transporter Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Fat Cell Differentiation Fibroblast Proliferation Negative Regulation Of Fibroblast Proliferation ERK1 And ERK2 Cascade Negative Regulation Of ERK1 And ERK2 Cascade	Intracellular Monoatomic Ion Homeostasis Regulation Of PH Amine Transport Epithelial Cell Differentiation Carbon Dioxide Transmembrane Transport Homeostatic Process Transepithelial Ammonium Transport Ammonium Transmembrane Transport Ammonium Homeostasis
Pathways			Rhesus glycoproteins mediate ammonium transport
Drugs
Diseases
GWAS			Body size at age 10 ( 32376654) Dentures ( 31235808) Femur bone mineral density x serum urate levels interaction ( 34046847) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
Interacting Genes		19 interacting genes: CD53 CERS4 FATE1 FNDC9 GOLM1 GPR152 IL10RA LEUTX MFF RHCG SCARA5 SGTA SGTB SLC38A1 SSMEM1 TMEM179B TMPRSS2 TRHR UBQLN2	13 interacting genes: ARLN C1QL4 CXCL9 ERMP1 FXYD6 GPR25 IGFBP5 MS4A13 TMEM60 TMEM97 TRARG1 UPK1B YIPF6
Entrez ID		338761	51458
HPRD ID		17350	16102
Ensembl ID		ENSG00000186897	ENSG00000140519
Uniprot IDs		A0A3B0INP7 Q86Z23	Q9UBD6
PDB IDs			3HD6
Enriched GO Terms of Interacting Partners?		Membrane TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of ERAD Pathway Identical Protein Binding Regulation Of ERAD Pathway Establishment Of Protein Localization To Organelle Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Interleukin-10 Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Thyrotropin-releasing Hormone Receptor Activity Ferritin Receptor Activity Protein Targeting
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