PCNT and TUBGCP3

Number of citations of the paper that reports this interaction (PubMedID 12221128)
36

Data Source:
HPRD (in vivo)

		PCNT	TUBGCP3
Description		pericentrin	tubulin gamma complex component 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Membrane Centriolar Satellite	Spindle Pole Gamma-tubulin Complex Cytoplasm Centrosome Centriole Microtubule Organizing Center Spindle Polar Microtubule Cytosol Cytoskeleton Microtubule Membrane
	Molecular Function	Protein Binding Calmodulin Binding Molecular Adaptor Activity	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	Microtubule Cytoskeleton Organization Microtubule Nucleation Mitotic Spindle Organization Signal Transduction Cilium Assembly Positive Regulation Of Intracellular Protein Transport	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Single Fertilization Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases		Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II) Seckel syndrome
GWAS		Heel bone mineral density ( 30598549) Pre-treatment viral load in HIV-1 infection ( 31219150) S100 calcium-binding protein levels ( 33227023) Treatment resistant depression ( 30468137)	Glycated hemoglobin levels ( 20858683)
Interacting Genes		65 interacting genes: AKAP6 AKAP9 ANKRD24 ARHGAP21 CALM1 CALM2 CCP110 CDK12 CEP55 CEP85L COL6A1 CYTH1 DISC1 DMXL2 DNM1 DNM2 DNM3 DST EIF4G3 FEZ1 HMOX2 HPRT1 HUWE1 KALRN KIF1A KIF5C MACF1 MADD MAP1LC3A MAP1LC3B MRFAP1 MYT1L NDUFV3 NECAB1 NIPBL ODF2L PARVB PCM1 PDE9A PFKL PKNOX1 PNISR RAC3 RPRD1A RRBP1 RTRAF S100B SEPTIN7 SH3BGR SHTN1 SPTAN1 SPTBN1 SPTBN2 SRGAP2 ST18 SYNE1 TP53BP1 TRAF3IP1 TUBG1 TUBGCP2 TUBGCP3 UTRN YWHAH YWHAZ YY1AP1	12 interacting genes: AKAP9 ARTN CDC16 CEBPA DNAJB6 IMMT LRBA PCNT PROZ RASA3 TUBG1 TUBG2
Entrez ID		5116	10426
HPRD ID		05804	10289
Ensembl ID		ENSG00000160299	ENSG00000126216
Uniprot IDs		O95613	A0A087WU06 B4DYP7 Q96CW5
PDB IDs			6V6B 6V6S 6X0U 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 8Q62 8RX1 8VRD 8VRJ 8VRK
Enriched GO Terms of Interacting Partners?		Cytoskeleton Microtubule Cell Projection Organelle Organization Cytoplasm Centrosome Microtubule Binding Cell Projection Organization Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Microtubule-based Process Actin Binding Centriole Cytoskeleton Organization Plasma Membrane Bounded Cell Projection Organization Spectrin Identical Protein Binding Microtubule Nucleation Gamma-tubulin Complex Cell Projection Assembly Cellular Component Assembly Transmembrane Transporter Binding Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Vesicle Scission Microtubule Minus-end Binding Ciliary Basal Body Microtubule Organizing Center Structural Constituent Of Cytoskeleton Transport Along Microtubule Microtubule Cytoskeleton Cytosol Plasma Membrane Bounded Cell Projection Assembly Organelle Localization Sarcomere Establishment Of Organelle Localization Cell Leading Edge Pericentriolar Material Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Actin Filament Binding Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Calcium Channel Complex Polar Microtubule Actin Filament-based Process Microtubule-based Transport Cadherin Binding Regulation Of Cellular Component Organization Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Transporter Inhibitor Activity	Microtubule Nucleation Microtubule Nucleator Activity Gamma-tubulin Ring Complex Gamma-tubulin Complex Mitotic Spindle Organization Centrosome Microtubule Cytoskeleton Organization Involved In Mitosis Meiotic Spindle Organization Pericentriolar Material Spindle Organization Microtubule Cytoskeleton Organization Mitotic Sister Chromatid Segregation Cytoskeleton Organization Sister Chromatid Segregation Spindle Microtubule Spindle Organelle Organization Nuclear Chromosome Segregation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Cytoplasmic Microtubule Cytoplasmic Microtubule Organization Response To Vitamin B2 C/EBP Complex Microtubule CHOP-C/EBP Complex Microtubule Organizing Center Cytoskeleton Microtubule-based Process Peyer's Patch Morphogenesis Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Chorion Development Dendritic Branch White Fat Cell Proliferation Glial Cell-derived Neurotrophic Factor Receptor Binding
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