METTL9 and GFER

		METTL9	GFER
Description		methyltransferase 9, His-X-His N1(pi)-histidine	growth factor, augmenter of liver regeneration
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GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Cytosol
	Molecular Function	Protein Binding Methyltransferase Activity Transferase Activity Protein-L-histidine N-pros-methyltransferase Activity	Protein Binding Growth Factor Activity Protein-disulfide Reductase Activity Oxidoreductase Activity Flavin-dependent Sulfhydryl Oxidase Activity Thiol Oxidase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Methylation	Liver Development Signal Transduction Mitochondrial Disulfide Relay System
Pathways			Mitochondrial protein import
Drugs			Flavin adenine dinucleotide
Diseases
GWAS		Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Serum immune biomarker levels ( 32066700) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)
Interacting Genes		4 interacting genes: CHMP6 CHRM4 GFER MYG1	11 interacting genes: ASCC2 BNIPL COPS2 COPS5 METTL9 MTRR NPIPA1 PLEKHF2 SMAD2 TXN YY1
Entrez ID		51108	2671
HPRD ID		16839	02954
Ensembl ID		ENSG00000197006	ENSG00000127554
Uniprot IDs		Q9H1A3	P55789
PDB IDs		7Y9C 7YF2 7YF3 7YF4 8GZE 8GZF	3MBG 3O55 3TK0 3U2L 3U2M 3U5S 4LDK
Enriched GO Terms of Interacting Partners?		ESCRT III Complex Assembly G Protein-coupled Acetylcholine Receptor Activity Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Flavin-dependent Sulfhydryl Oxidase Activity Thiol Oxidase Activity Mitochondrial Disulfide Relay System Protein-disulfide Reductase Activity Locomotory Exploration Behavior Exploration Behavior 3'-5'-RNA Exonuclease Activity Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Peptidyl-tyrosine Phosphorylation Plasma Membrane Repair Mitotic Cytokinetic Process ESCRT III Complex Regulation Of Signaling Receptor Activity Multivesicular Body Membrane Viral Budding From Plasma Membrane Negative Regulation Of Signaling Receptor Activity Multivesicular Body Organization Amphisome Membrane Late Endosome To Lysosome Transport Lysosomal Membrane Organization Vesicle Fusion With Vacuole Kinetochore Microtubule Viral Budding Regulation Of Exosomal Secretion Negative Regulation Of ERBB Signaling Pathway Vesicle Budding From Membrane Nuclear Membrane Reassembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Viral Release From Host Cell Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Protein Tyrosine Kinase Activity Multivesicular Body Assembly Midbody Abscission Regulation Of Spindle Assembly Multivesicular Body-lysosome Fusion Regulation Of Protein Tyrosine Kinase Activity Late Endosome To Vacuole Transport Cytokinetic Process Acetylcholine Receptor Signaling Pathway Mitochondrial RNA Metabolic Process Membrane Fission Regulation Of Mitotic Spindle Organization Endosome Transport Via Multivesicular Body Sorting Pathway	Protein Deneddylation Protein Neddylation Regulation Of Protein Neddylation COP9 Signalosome SMAD Binding Oxidoreductase Activity, Acting On Metal Ions, NAD Or NADP As Acceptor [methionine Synthase] Reductase (NADPH) Activity Protein-L-histidine N-pros-methyltransferase Activity
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