VPS36 and RILP

Number of citations of the paper that reports this interaction (PubMedID 17010938)
0

Data Source:
BioGRID (pull down)

		VPS36	RILP
Description		vacuolar protein sorting 36 homolog	Rab interacting lysosomal protein
Image
GO Annotations	Cellular Component	ESCRT II Complex Nucleus Cytoplasm Lysosome Endosome Late Endosome Cytosol Membrane Late Endosome Membrane Extracellular Exosome	Cytoplasm Lysosome Lysosomal Membrane Endosome Late Endosome Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Late Endosome Membrane Protein-containing Complex Ciliary Basal Body
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol-3-phosphate Binding Ubiquitin Binding	Protein Binding Small GTPase Binding Protein Dimerization Activity Dynein Light Intermediate Chain Binding
	Biological Process	Protein Transport Macroautophagy Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Fission	Endosome To Lysosome Transport Protein Transport Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Protein Catabolic Process Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Cilium Assembly Intralumenal Vesicle Formation
Pathways		Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events	MHC class II antigen presentation
Drugs
Diseases
GWAS		Lewy body disease ( 25188341)
Interacting Genes		8 interacting genes: CHMP6 RILP SNCA SNF8 SPRY2 TSG101 UBC VPS25	12 interacting genes: KPNA2 LDB2 RAB34 RAB7A RCHY1 SNF8 VPS11 VPS16 VPS18 VPS36 VPS39 VPS41
Entrez ID		51028	83547
HPRD ID		12620	09706
Ensembl ID		ENSG00000136100	ENSG00000167705
Uniprot IDs		Q86VN1	Q96NA2
PDB IDs		2HTH 2ZME 3CUQ	1YHN
Enriched GO Terms of Interacting Partners?		Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Sorting Pathway Endosome Organization Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Organization Multivesicular Body Assembly Late Endosome To Vacuole Transport Membrane Fission Vacuolar Transport Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Signaling Receptor Activity Regulation Of ERBB Signaling Pathway Regulation Of Phosphorus Metabolic Process Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Protein Metabolic Process Endosomal Transport Regulation Of Exosomal Secretion Endosome Membrane Membrane Organization Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Protein Tyrosine Kinase Activity Vesicle Organization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Protein Phosphorylation Establishment Of Localization In Cell Negative Regulation Of ERBB Signaling Pathway Regulation Of Signaling Receptor Activity Late Endosome Membrane Regulation Of Phosphorylation Macroautophagy ESCRT II Complex Regulation Of Exocytosis Vesicle-mediated Transport Regulation Of Protein Kinase Activity Establishment Of Protein Localization To Vacuole Regulation Of Kinase Activity Regulation Of Protein Modification Process Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Exocytosis Autophagy Organelle Assembly Endosome Protein Localization To Vacuole Organelle Organization Negative Regulation Of Protein Phosphorylation	Vesicle Organization Late Endosome Membrane Vacuolar Transport Organelle Membrane Fusion Vesicle Fusion Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion HOPS Complex Endosome To Lysosome Transport Organelle Fusion Autophagy Late Endosome Membrane Fusion Intracellular Protein Transport Membrane Organization Protein Transport Lysosomal Transport Endosome Membrane Establishment Of Protein Localization Cellular Localization Vesicle-mediated Transport Endosome Intracellular Transport Intracellular Protein Localization Lysosome CORVET Complex AP-3 Adaptor Complex Establishment Of Localization In Cell Establishment Of Protein Localization To Vacuole Lysosomal Membrane Clathrin-coated Vesicle Organelle Organization Endosome Organization Protein Localization To Vacuole Catabolic Process Lysosomal HOPS Complex Endosomal Transport ESCRT II Complex Vesicle-mediated Transport To The Plasma Membrane Establishment Of Protein Localization To Organelle Vesicle Tethering Complex Macroautophagy Vacuole Organization Regulation Of Protein-containing Complex Assembly Positive Regulation Of Protein Catabolic Process Cytoplasmic Vesicle Endocytic Recycling Autophagosome Phagosome Maturation Membrane Docking
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