GLRX2 and NUTF2

		GLRX2	NUTF2
Description		glutaredoxin 2	nuclear transport factor 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion	Nucleus Nuclear Inner Membrane Nuclear Outer Membrane Nuclear Pore Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Arsenate Reductase (glutaredoxin) Activity Electron Transfer Activity Protein-disulfide Reductase Activity Glutathione Disulfide Oxidoreductase Activity Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding	Protein Binding Structural Constituent Of Nuclear Pore Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Regulation Of DNA-templated Transcription Glutathione Metabolic Process Apoptotic Process Response To Temperature Stimulus Regulation Of Signal Transduction Cell Differentiation DNA Protection Cell Redox Homeostasis Response To Redox State	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Protein Transport MRNA Transport Protein Localization To Nuclear Pore
Pathways
Drugs		Glutathione
Diseases
GWAS			Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		6 interacting genes: DCXR DENND1B ELF5 FBXO7 NUTF2 TXNRD1	54 interacting genes: BEND7 BRWD1 CAMK2G CANX CCDC106 CCDC150 CCDC158 CEBPA CHCHD3 CHMP4A CKMT1A CKMT1B CLPP FAM50B GLRX2 HMG20A HMG20B KHDC4 KRT86 KRTAP9-8 LASP1 LCE1C LCE5A LENG1 LUC7L2 MRNIP MYOZ3 NFAT5 NME1 NME4 NRIP3 NUP54 NUP62 PAX4 PBX4 PCNA PFKP PHF11 PPP1R16A PTMA RAN RPRD1B SF3B3 SPATC1L SPRY4 TERF2 TEX35 THAP11 THAP3 TLE5 UBAP2 WWP2 YAF2 ZMAT2
Entrez ID		51022	10204
HPRD ID		12112	12050
Ensembl ID		ENSG00000023572	ENSG00000102898
Uniprot IDs		Q9NS18	P61970
PDB IDs		2CQ9 2FLS 2HT9	1GY5
Enriched GO Terms of Interacting Partners?		NADPH Peroxidase Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite L-xylulose Reductase (NADPH) Activity Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Ectodermal Cell Fate Commitment Xylulose Metabolic Process Protein Localization To Nuclear Pore Lewy Body Core D-xylose Metabolic Process Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, NAD(P) As Acceptor Oxidoreductase Activity, Acting On CH-OH Group Of Donors D-glucuronate Catabolic Process D-glucuronate Catabolic Process To D-xylulose 5-phosphate Nuclear Pore Central Transport Channel Thioredoxin-disulfide Reductase (NADPH) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Carbonyl Reductase (NADPH) Activity Positive Regulation Of T-helper 2 Cell Cytokine Production Pentose Metabolic Process	Protein Binding Protein-containing Complex Binding Phosphocreatine Biosynthetic Process Creatine Kinase Activity GTP Metabolic Process Nuclear Pore Nuclear Pore Central Transport Channel Nucleus UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process Nucleoplasm Protein Hexamerization Negative Regulation Of Protein Sumoylation Male Germ Cell Nucleus CTP Biosynthetic Process CTP Metabolic Process
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