NFX1 and ELAVL4

Number of citations of the paper that reports this interaction (PubMedID 15358174)
0

Data Source:
HPRD (in vitro, in vivo)

		NFX1	ELAVL4
Description		nuclear transcription factor, X-box binding 1	ELAV like RNA binding protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane	Cytoplasm Axon Dendrite Growth Cone Cell Projection Perikaryon Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Nucleic Acid Binding DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Nucleic Acid Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) Binding MRNA 3'-UTR AU-rich Region Binding Pre-mRNA Intronic Pyrimidine-rich Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Inflammatory Response Protein Ubiquitination Negative Regulation Of MHC Class II Biosynthetic Process Protein Autoubiquitination	RNA Processing MRNA Processing Learning Locomotory Behavior RNA Splicing Cerebral Cortex Neuron Differentiation Dendrite Morphogenesis 3'-UTR-mediated MRNA Stabilization Positive Regulation Of 3'-UTR-mediated MRNA Stabilization
Pathways
Drugs
Diseases
GWAS		Fasting glucose ( 34059833)	Alcohol consumption ( 31358974) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 25673413 26961502) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Male-pattern baldness ( 28196072) Obesity-related traits ( 23251661) Schizophrenia ( 30285260) Smoking status (ever vs never smokers) ( 30643258) Tea consumption ( 31046077)
Interacting Genes		8 interacting genes: CDKN2A ELAVL4 MAML3 PPP1R16B SIGMAR1 UBC UBE2N UBE3A	6 interacting genes: ELAVL2 EWSR1 GAP43 NFX1 NXF1 PHF20L1
Entrez ID		4799	1996
HPRD ID		11936	01343
Ensembl ID		ENSG00000086102	ENSG00000162374
Uniprot IDs		Q12986	A0A0R4J2E6 A0A494C0M6 A0A494C147 A0A494C1D9 B1APY9 P26378
PDB IDs			1FXL 1G2E
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Post-translational Protein Modification Protein Modification By Small Protein Conjugation Protein Ubiquitination Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification Protein Polyubiquitination Post-translational Protein Modification Ligase Inhibitor Activity Negative Regulation Of TORC1 Signaling Sperm Entry Positive Regulation Of Golgi Lumen Acidification Protein K63-linked Ubiquitination Positive Regulation Of Protein Modification Process Negative Regulation Of TOR Signaling Pre-mRNA Intronic Pyrimidine-rich Binding Regulation Of TORC1 Signaling Positive Regulation Of Protein Ubiquitination Positive Regulation Of Macrophage Apoptotic Process Apoptotic Process Involved In Mammary Gland Involution UBC13-MMS2 Complex Regulation Of Golgi Lumen Acidification Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Senescence-associated Heterochromatin Focus Growth Cone Modification-dependent Protein Catabolic Process Ubiquitin Conjugating Enzyme Complex Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Immature T Cell Proliferation In Thymus Regulation Of TOR Signaling Positive Regulation Of Cellular PH Reduction Mitochondrial Depolarization Oncogene-induced Cell Senescence Negative Regulation Of Immature T Cell Proliferation Positive Regulation Of Apoptotic Process Involved In Morphogenesis Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Modification Process RNA Binding Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Protein Localization To Lysosome G Protein-coupled Opioid Receptor Activity Myosin Phosphatase Regulator Activity Positive Regulation Of Transcription Of Notch Receptor Target Positive Regulation Of Apoptotic Process Involved In Development Positive Regulation Of Protein K63-linked Ubiquitination Protein Modification Process Negative Regulation Of Ubiquitin Protein Ligase Activity Positive Regulation Of Myeloid Cell Apoptotic Process	Nucleic Acid Binding
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