ELAVL4 and PHF20L1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		ELAVL4	PHF20L1
Description		ELAV like RNA binding protein 4	PHD finger protein 20 like 1
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GO Annotations	Cellular Component	Cytoplasm Axon Dendrite Growth Cone Cell Projection Perikaryon Ribonucleoprotein Complex	Nucleus Nucleoplasm NSL Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) Binding MRNA 3'-UTR AU-rich Region Binding Pre-mRNA Intronic Pyrimidine-rich Binding	Protein Binding Zinc Ion Binding Metal Ion Binding Methylation-dependent Protein Binding
	Biological Process	RNA Processing MRNA Processing Learning Locomotory Behavior RNA Splicing Cerebral Cortex Neuron Differentiation Dendrite Morphogenesis 3'-UTR-mediated MRNA Stabilization Positive Regulation Of 3'-UTR-mediated MRNA Stabilization	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Catabolic Process
Pathways			Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 25673413 26961502) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Male-pattern baldness ( 28196072) Obesity-related traits ( 23251661) Schizophrenia ( 30285260) Smoking status (ever vs never smokers) ( 30643258) Tea consumption ( 31046077)	Body fat percentage ( 31752434) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483) Thyroid stimulating hormone levels ( 32769997) Type 1 diabetes (age at diagnosis) ( 33179336)
Interacting Genes		6 interacting genes: ELAVL2 EWSR1 GAP43 NFX1 NXF1 PHF20L1	10 interacting genes: APP CASP10 ELAVL4 KDM1A LRRK2 LYAR TERT UBC WWP1 ZNF471
Entrez ID		1996	51105
HPRD ID		01343	15125
Ensembl ID		ENSG00000162374	ENSG00000129292
Uniprot IDs		A0A0R4J2E6 A0A494C0M6 A0A494C147 A0A494C1D9 B1APY9 P26378	A0A0A0MQS0 A0A0A8K9A6 A8MW92 F8W9L8 Q9H8G4
PDB IDs		1FXL 1G2E	2EQM 2EQU 2JTF 6L0X 6L10 6L1C 6L1F 6L1I 6L1P
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding	Golgi-associated Vesicle Growth Cone Cellular Response To Catecholamine Stimulus Cellular Response To Manganese Ion Perikaryon Regulation Of Apoptotic Signaling Pathway Response To Catecholamine Response To Manganese Ion Macromolecule Metabolic Process Positive Regulation Of Endocytosis Telomeric DNA Binding Neuron Maturation Regulation Of Intrinsic Apoptotic Signaling Pathway Locomotory Behavior Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Amyloid-beta Complex Cell Projection Morphogenesis Growth Cone Lamellipodium Regulation Of Neuron Apoptotic Process Regulation Of Response To Calcium Ion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Amylin Binding Neuron Projection Morphogenesis Positive Regulation Of Toll Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Cellular Response To CAMP Modulation Of Excitatory Postsynaptic Potential TERT-RMRP Complex Template-free RNA Nucleotidyltransferase Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Transdifferentiation RNA-directed RNA Polymerase Complex Positive Regulation Of Stem Cell Proliferation SiRNA Transcription Regulation Of Neuroblast Proliferation Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Myeloid Cell Development Negative Regulation Of RNA Metabolic Process Regulation Of Endocytosis Regulation Of Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Regulation Of Wnt Signaling Pathway Acetylcholine Receptor Activator Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Response To Metal Ion
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