NASP and ULK2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NASP	ULK2
Description		nuclear autoantigenic sperm protein	unc-51 like autophagy activating kinase 2
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex	Phagophore Assembly Site Cytoplasm Autophagosome Cytosol Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Phagophore Assembly Site Membrane
	Molecular Function	Protein Binding Histone Binding Protein-containing Complex Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Blastocyst Development DNA Replication Nucleosome Assembly DNA Replication-dependent Chromatin Assembly Male Gonad Development Protein Transport Response To Testosterone CENP-A Containing Chromatin Assembly	Autophagosome Assembly Mitophagy Autophagy Signal Transduction Nervous System Development Axonogenesis Axon Guidance Intracellular Protein Localization Regulation Of Autophagy Piecemeal Microautophagy Of The Nucleus Response To Starvation Protein Autophosphorylation Collateral Sprouting Negative Regulation Of Collateral Sprouting Axon Extension Reticulophagy Somatic Sensory System Development
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		23 interacting genes: CDC42 FXR2 H1-1 H1-2 H3-3B H3-4 H3-5 H3C10 H3C13 H3C14 H3C4 H3C8 HDAC6 ITSN1 LUC7L2 MTNR1A OGT PTK2 ST3GAL3 TERF2 TERF2IP TIAM1 ULK2	16 interacting genes: ATG14 DIXDC1 DUXAP9 EEF1B2 GABARAP GABARAPL2 LNX1 LUC7L2 NASP POLA2 RAI1 SETDB1 SQSTM1 SYNGAP1 TNPO1 ZNF32
Entrez ID		4678	9706
HPRD ID		04423	10556
Ensembl ID		ENSG00000132780	ENSG00000083290
Uniprot IDs		P49321 Q5T626	Q8IYT8
PDB IDs		7V1K 7V1L 7V1M 7V6P 7V6Q	6QAT 6QAU 6QAV 6YID
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Chromatin Nucleosome Nucleosome Assembly Nucleosome Organization Protein-DNA Complex Assembly Chromosome Protein-containing Complex Organization Protein Heterodimerization Activity Protein-containing Complex Assembly Cellular Component Assembly Chromatin Organization Chromatin Remodeling Chromosome Organization Telomere Organization Nucleosomal DNA Binding Negative Regulation Of DNA Recombination Epigenetic Regulation Of Gene Expression Negative Regulation Of DNA Recombination At Telomere Regulation Of Cellular Component Organization Shelterin Complex Organelle Organization Negative Regulation Of Cellular Component Organization Negative Regulation Of DNA Metabolic Process DNA Binding Regulation Of DNA Recombination Protection From Non-homologous End Joining At Telomere Gene Expression Protein-containing Complex Macromolecule Biosynthetic Process Nuclear Telomere Cap Complex Mitophagy Euchromatin Nucleus G-rich Strand Telomeric DNA Binding Chromosome, Telomeric Region Protein Localization To Chromosome, Telomeric Region Nucleoplasm Telomere Capping Autophagy Of Mitochondrion Telomere Maintenance In Response To DNA Damage Negative Regulation Of Chromosome Organization Regulation Of Cell Growth Chromatin DNA Binding Collateral Sprouting Dendritic Spine Morphogenesis Positive Regulation Of Cellular Component Organization RNA-templated DNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Telomeric DNA Binding Negative Regulation Of Protein-containing Complex Assembly	Mitophagy Autophagosome Autophagy Of Mitochondrion Response To Mitochondrial Depolarisation Macroautophagy Autophagosome Maturation Autophagosome Membrane Protein Transport Cellular Response To Nitrogen Starvation Intracellular Protein Localization Establishment Of Protein Localization Phosphatidylethanolamine Binding Autophagosome Assembly Regulation Of Protein Complex Stability GABA Receptor Binding Autophagosome Organization Autophagy Protein Import Into Nucleus Import Into Nucleus Protein Localization To Organelle Establishment Of Protein Localization To Organelle Protein-containing Complex Disassembly Phagophore Assembly Site Vacuole Organization Protein Localization To Nucleus Cellular Response To Starvation Beta-tubulin Binding Regulation Of Ras Protein Signal Transduction Protein Targeting Sperm Midpiece Extrinsic Component Of Phagophore Assembly Site Membrane Protein Targeting To Vacuole Response To Starvation Intracellular Protein Transport Nuclear Transport Nucleocytoplasmic Transport Synapse Organization Establishment Of Protein Localization To Vacuole Cellular Response To Nutrient Levels Brown Fat Cell Proliferation Amphisome Extrinsic Component Of Omegasome Membrane Regulation Of Small GTPase Mediated Signal Transduction Ubiquitin Protein Ligase Binding Positive Regulation Of Protein K48-linked Ubiquitination Protein Localization To Vacuole Eukaryotic Translation Elongation Factor 1 Complex Organelle Assembly Histone H3K9 Trimethyltransferase Activity
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